{"id":"W1966543415","doi":"10.1016/j.bbagen.2009.05.007","title":"Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy","year":2009,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Aging","funders":"Institute on Aging, College of Medicine, University of Florida; National Institute on Aging; University of Florida","keywords":"Sarcopenia; Mitochondrion; Atrophy; Muscle atrophy; Apoptosis; Oxidative stress; Skeletal muscle; Myocyte; Cell biology; Biology; Pathogenesis; Medicine; Internal medicine; Endocrinology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001327781,0.001184648,0.001678462,0.0001864164,0.0002516688,0.0001287607,0.0008217791,0.0008709219,0.00001358111],"category_scores_gemma":[0.0001849515,0.001028522,0.0008060705,0.0004047628,0.0002091153,0.00001980578,0.0005475704,0.0005071045,0.00009190944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005573997,"about_ca_system_score_gemma":0.0003293653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006333151,"about_ca_topic_score_gemma":0.00003388575,"domain_scores_codex":[0.9957303,0.0005620781,0.0006636169,0.001866868,0.0002813638,0.0008957871],"domain_scores_gemma":[0.9977043,0.0001020431,0.0003977653,0.001253492,0.00007823914,0.0004642049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004708153,0.0003095494,5.330077e-7,0.001612608,0.0003902939,0.00001423877,0.00005648558,0.000003984283,0.8685877,0.0001087958,0.009485167,0.1189598],"study_design_scores_gemma":[0.001498427,0.002598058,0.0005443267,0.001786616,0.0008760815,0.00002897142,0.000006450739,0.000005370471,0.0873104,0.0002172403,0.9025611,0.002566955],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.466858,0.5301835,0.00002121533,0.0001731928,0.0006141507,0.001602356,0.0002246586,0.0000722025,0.0002507236],"genre_scores_gemma":[0.03563233,0.9571952,0.001213666,0.0009747613,0.002437698,0.0002813099,0.001627601,0.0001925017,0.0004448982],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8930759,"threshold_uncertainty_score":0.9992165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893742285585762,"score_gpt":0.3054783110079783,"score_spread":0.2865408881521207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}