{"id":"W1966593127","doi":"10.1515/bc.2006.083","title":"The kallikrein world: an update on the human tissue kallikreins","year":2006,"lang":"en","type":"review","venue":"Biological Chemistry","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Mount Sinai Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Kallikrein; Proteases; Human genome; Computational biology; Biology; Function (biology); Cancer; Gene; Genome; Genetics; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000469579,0.000636364,0.001212448,0.00003211517,0.0005681713,0.0001071779,0.0007199653,0.0006174379,0.0009791845],"category_scores_gemma":[0.0001737596,0.0002726431,0.0005769509,0.0003260085,0.0004428874,0.00002252473,0.0001342188,0.0008085254,0.0002069192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001228812,"about_ca_system_score_gemma":0.0001310723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002493599,"about_ca_topic_score_gemma":0.0000148993,"domain_scores_codex":[0.9974852,0.0001589528,0.0007729943,0.0007120228,0.0003198536,0.0005509354],"domain_scores_gemma":[0.9976913,0.00056032,0.0003845308,0.001085542,0.00006884368,0.0002094189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005198281,0.0005821233,0.0001839697,0.003070085,0.0003787387,0.0001499038,0.00001622014,8.121619e-7,0.0005691905,0.009547721,0.0410967,0.9443526],"study_design_scores_gemma":[0.0001669588,0.0001063306,0.0001652627,0.001457245,0.0002686926,0.00004354678,0.000007042059,0.000001681728,0.0004920368,0.0004680338,0.9964617,0.0003614835],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00101675,0.9798473,0.000002459802,0.0006928385,0.0001242727,0.0007126296,0.00006309009,0.0001938295,0.01734679],"genre_scores_gemma":[0.002592775,0.9666519,0.00002919061,0.0005149754,0.002328139,0.0001780038,0.00199054,0.00006674918,0.02564772],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.955365,"threshold_uncertainty_score":0.9999726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1004005098187019,"score_gpt":0.3710585388055498,"score_spread":0.2706580289868479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}