{"id":"W1966820779","doi":"10.1111/j.1744-7410.2007.00080.x","title":"HSP90 and MAPK activation are required for ampulla development in the direct‐developing ascidian <i>Molgula pacifica</i>","year":2007,"lang":"en","type":"article","venue":"Invertebrate Biology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Biology; Cell biology; MAPK/ERK pathway; Heat shock protein; Cytoskeleton; Actin; Hsp90; Geldanamycin; Progenitor cell; Kinase; Molecular biology; Cell; Stem cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001316639,0.0001642112,0.0001734864,0.0001077457,0.0001590629,0.00002811853,0.0002362901,0.0002834062,0.00000429137],"category_scores_gemma":[0.0003145828,0.0001257089,0.00003315808,0.0001785704,0.0001275934,0.000006736743,0.0001099618,0.0001144673,0.000006576354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005476866,"about_ca_system_score_gemma":0.0001746062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006587632,"about_ca_topic_score_gemma":0.0008977396,"domain_scores_codex":[0.9985234,0.0001680526,0.0002963363,0.0004330624,0.00009373199,0.0004853809],"domain_scores_gemma":[0.999422,0.00008302267,0.00007458495,0.0002570216,0.00009383636,0.00006954676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001564335,0.00003389651,0.01530099,0.00003978447,0.00003191964,0.000004975423,0.0002797159,8.460353e-7,0.9630268,0.0006276899,0.0008621876,0.01963476],"study_design_scores_gemma":[0.0006130175,0.0001492824,0.01421982,0.0000273412,0.000002240474,0.00001026261,0.0002687327,0.00004046536,0.8458773,0.0003863592,0.1381816,0.0002236376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860127,0.0002612204,0.01060114,0.001351989,0.00008930644,0.0007898579,0.000009687267,0.00001390241,0.0008702031],"genre_scores_gemma":[0.9953598,0.00007603929,0.002795907,0.0011405,0.0001315737,0.0001521502,0.0001729232,0.0000192555,0.0001518054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1373194,"threshold_uncertainty_score":0.5126261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03818925723187503,"score_gpt":0.310700629605239,"score_spread":0.2725113723733639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}