{"id":"W1966827753","doi":"10.1097/01.mpa.0000335346.58579.02","title":"NIC/CSL TRANSCRIPTIONAL ACTIVITY IS REGULATED BY THE MEK/ERK PATHWAY IN HUMAN PANCREATIC CANCER CELLS","year":2008,"lang":"en","type":"article","venue":"Pancreas","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"MAPK/ERK pathway; Notch signaling pathway; MEK inhibitor; Cell biology; Chemistry; Transcriptional regulation; Signal transduction; Cancer research; Biology; Molecular biology; Transcription factor; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009890427,0.0002114502,0.0001765592,0.0002224284,0.0001645473,0.0002883053,0.0001094076,0.000124062,0.001256874],"category_scores_gemma":[0.00009257161,0.0001035844,0.0002006851,0.0002957557,0.0001449536,0.00009678277,0.0001433916,0.0003391857,0.0005135219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000324434,"about_ca_system_score_gemma":0.0002901548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001277928,"about_ca_topic_score_gemma":0.001267366,"domain_scores_codex":[0.9998671,0.00001624675,0.00001633044,0.00002640827,0.00004602821,0.0000279355],"domain_scores_gemma":[0.9999568,0.000008824211,0.000007732207,0.000007218718,0.00001116992,0.000008173313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005674551,0.00009927926,0.001530666,0.0001260701,0.00001211117,0.0001207414,0.00006357679,0.0001825905,0.9934605,0.0001373373,0.0002231646,0.003476487],"study_design_scores_gemma":[0.00002407882,0.0002302066,0.01502671,0.000007043704,0.00002434217,0.0004882688,0.00007458122,0.001622675,0.9764032,0.00003113732,0.00606126,0.000006452943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898642,0.002821003,0.002446233,0.0001222262,0.00003205647,0.00003928626,0.00137849,0.0001030794,0.003193302],"genre_scores_gemma":[0.9887792,0.001794312,0.002545913,0.0000423447,0.00001141033,0.00009965474,0.002745341,0.000013198,0.003968578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277928,"threshold_uncertainty_score":0.00420469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01393388683638695,"score_gpt":0.2435394364396972,"score_spread":0.2296055496033103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}