{"id":"W1966849099","doi":"10.1074/jbc.m313384200","title":"From Structure and Dynamics of Protein L7/L12 to Molecular Switching in Ribosome","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Antiparallel (mathematics); Ribosomal protein; Ribosome; Dimer; Crystallography; Ribosomal RNA; Nuclear magnetic resonance spectroscopy; Protein structure; Chemistry; Biophysics; Biology; Stereochemistry; Physics; Biochemistry; RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001698046,0.0001415489,0.0002705019,0.00002461152,0.00001677713,0.00001186384,0.0002217205,0.0002937858,0.00002390386],"category_scores_gemma":[0.0002415129,0.0001057986,0.00008550836,0.0000680248,0.00003754667,0.000003941912,0.00009786968,0.000178626,3.007596e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002924787,"about_ca_system_score_gemma":0.00004987452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000173926,"about_ca_topic_score_gemma":0.000003909649,"domain_scores_codex":[0.9991125,0.00003384444,0.0003775569,0.0001989683,0.0001209645,0.0001561874],"domain_scores_gemma":[0.9994356,0.00001175372,0.0002261121,0.0001519509,0.00006159894,0.0001130092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001640317,0.00004118919,0.0006450632,0.00001920834,0.00002677886,0.00003017599,0.00002504086,0.0001357725,0.9974011,0.00004615682,0.000001442923,0.001464063],"study_design_scores_gemma":[0.0005022111,0.0002680027,0.0007152069,0.0001040267,0.000007029683,0.0000467955,0.00008388396,0.000004367906,0.9882076,0.009857718,0.00007523313,0.0001279742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942156,0.0007166424,0.004495285,0.0003591866,0.00002787417,0.0001012892,0.00003222439,0.000002046311,0.00004986594],"genre_scores_gemma":[0.9927511,0.00004365631,0.006956896,0.00008285629,0.0001308123,0.000002651727,0.00001491669,0.000008880479,0.000008224045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009811561,"threshold_uncertainty_score":0.4314342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007132974977031544,"score_gpt":0.2274064773587188,"score_spread":0.2202735023816872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}