{"id":"W1966905733","doi":"10.1038/cgt.2009.83","title":"CUG2, a novel oncogene confers reoviral replication through Ras and p38 signaling pathway","year":2010,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Oncolytic virus; MAPK/ERK pathway; Oncogene; Transfection; Biology; Cancer research; Apoptosis; Cell biology; p38 mitogen-activated protein kinases; Cancer cell; Kinase; Molecular biology; Cell cycle; Cell culture; Cancer; Tumor cells","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001904233,0.0006654102,0.0003096794,0.0006137181,0.0004537922,0.0004859345,0.0004476946,0.0004336652,0.001465584],"category_scores_gemma":[0.0001350684,0.0002147016,0.0002968671,0.0002925595,0.0003668747,0.000403579,0.0003178616,0.0007682487,0.0003789848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007745764,"about_ca_system_score_gemma":0.0004084518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001352759,"about_ca_topic_score_gemma":0.001646835,"domain_scores_codex":[0.9998037,0.0000317383,0.00001208883,0.00004871835,0.00004400514,0.00005986474],"domain_scores_gemma":[0.9999068,0.00001596689,0.00002038766,0.00002029995,0.000007943238,0.00002861528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009809615,0.000039637,0.00008664108,0.00002180244,0.000004406556,0.00009110326,0.00001518822,0.00005383228,0.9981187,0.0004523279,0.0001192744,0.0008990163],"study_design_scores_gemma":[0.00001919971,0.0001336922,0.0006282742,0.000002728719,0.00001367363,0.0004186733,0.00001752901,0.0008875545,0.9942843,0.00007622888,0.003512027,0.000006093337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881268,0.001597485,0.006024034,0.000195097,0.00008487791,0.00007108525,0.0004983188,0.0004282581,0.002974101],"genre_scores_gemma":[0.9905723,0.0003993624,0.004055711,0.00003684395,0.00001588415,0.00005028379,0.0008141719,0.00005916364,0.003996251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001465584,"threshold_uncertainty_score":0.005620003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04073859269605616,"score_gpt":0.3403672380068577,"score_spread":0.2996286453108015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}