{"id":"W1967084106","doi":"10.1074/jbc.m313333200","title":"Regulation of Angiotensin II Type 1A Receptor Intracellular Retention, Degradation, and Recycling by Rab5, Rab7, and Rab11 GTPases","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Endosome; Endocytic cycle; Intracellular; Cell biology; Endocytosis; Internalization; Receptor; Rab; GTPase; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001905457,0.0002084281,0.0002077091,0.0001885783,0.0001649328,0.0004852171,0.0001401534,0.0002071168,0.0003777926],"category_scores_gemma":[0.0001446164,0.0001310362,0.000297354,0.00009847317,0.0002132664,0.0002018192,0.0001722114,0.000312259,0.0002127457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000531837,"about_ca_system_score_gemma":0.0002591027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001211274,"about_ca_topic_score_gemma":0.001237761,"domain_scores_codex":[0.9997702,0.00005981342,0.00001808464,0.00002919255,0.00004952289,0.00007304171],"domain_scores_gemma":[0.9999106,0.0000156831,0.000023603,0.000006964963,0.00001687722,0.00002624561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001624332,0.00002929369,0.0005385412,0.00003402863,0.00001012145,0.00007898014,0.00001895493,0.00009472168,0.9970031,0.0002504988,0.00003379017,0.001745519],"study_design_scores_gemma":[0.0000373314,0.0002376684,0.02267288,0.00001022581,0.00005325667,0.00041667,0.0001162249,0.005377377,0.9683176,0.0001305561,0.002615869,0.0000144935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955202,0.002653735,0.0007261111,0.00007064581,0.00001174141,0.000008439345,0.00004348748,0.00003012594,0.0009353583],"genre_scores_gemma":[0.9968393,0.001163166,0.0008309984,0.00003592124,0.000005604603,0.00001762332,0.0000832579,0.00001023236,0.001013827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001211274,"threshold_uncertainty_score":0.003858745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01335770590205684,"score_gpt":0.2136707567089688,"score_spread":0.200313050806912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}