{"id":"W1967101890","doi":"10.1002/art.33353","title":"Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: Results of a forty‐eight–week randomized, double‐blind, placebo‐controlled, parallel‐group phase III trial","year":2012,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Center for Research Resources","keywords":"Medicine; Ocrelizumab; Rheumatoid arthritis; Placebo; Internal medicine; Rheumatology; Adverse effect; Arthritis; Methotrexate; Pathology; Rituximab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003026202,0.001121007,0.002548483,0.0002351708,0.0004359839,0.0007524216,0.0006157981,0.001359013,0.002114737],"category_scores_gemma":[0.001888562,0.0005320322,0.00140833,0.0002626354,0.0008954054,0.0006234343,0.0002312285,0.00164125,0.0004679907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004619256,"about_ca_system_score_gemma":0.0009287188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003686299,"about_ca_topic_score_gemma":0.0006729093,"domain_scores_codex":[0.9991417,0.0004462409,0.00008271113,0.0001437332,0.00009511244,0.00009048391],"domain_scores_gemma":[0.9982955,0.0004667382,0.0005007246,0.0001503159,0.0001231578,0.0004635406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9531639,0.009825964,0.003380602,0.0005058761,0.000988645,0.00007851084,0.00008383642,0.0002619807,0.008615562,0.00003507878,0.00037948,0.02268043],"study_design_scores_gemma":[0.8893244,0.1021747,0.006272933,0.00002359106,0.0005158424,0.00009281623,0.00001728929,0.0003018846,0.000815327,0.000034029,0.0004158558,0.00001109936],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954813,0.002543454,0.0003356408,0.0002314298,0.0000946602,0.0006583208,0.0001975166,0.00003288978,0.0004247076],"genre_scores_gemma":[0.9956552,0.001103538,0.0009183923,0.0004052631,0.0002395935,0.0007847402,0.0003938139,0.00001059376,0.0004887267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003026202,"threshold_uncertainty_score":0.01600426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0175188673964018,"score_gpt":0.2739853887195389,"score_spread":0.2564665213231371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}