{"id":"W1967120431","doi":"10.1038/sj.npp.1301145","title":"Role of α1-Adrenoceptors of the Locus Coeruleus in Self-Stimulation of the Medial Forebrain Bundle","year":2006,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; York University","keywords":"Locus coeruleus; Medial forebrain bundle; Agonist; Stimulation; Phenylephrine; Endocrinology; Prazosin; Alpha (finance); Internal medicine; Chemistry; Forebrain; Receptor; Psychology; Neuroscience; Dopamine; Central nervous system; Biology; Dopaminergic; Medicine; Antagonist; Developmental psychology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181414,0.0001671976,0.000192253,0.0001537901,0.0002197821,0.0003013679,0.0002165354,0.000207121,0.0009181739],"category_scores_gemma":[0.0001655673,0.00008306125,0.0001421765,0.00005284302,0.0002738611,0.0002409227,0.0001393066,0.0003711051,0.0001530562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000433615,"about_ca_system_score_gemma":0.0001896669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001578649,"about_ca_topic_score_gemma":0.002475947,"domain_scores_codex":[0.9999306,0.00001512583,0.00000377884,0.000009824167,0.00001703695,0.00002358455],"domain_scores_gemma":[0.9998651,0.00002177678,0.0000281416,0.0000154661,0.0000213899,0.00004820298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002011749,0.00002062519,0.0008356024,0.00001762458,0.000007316426,0.0001823248,0.00003229917,0.00005608679,0.9958596,0.0006096999,0.00002249109,0.002155123],"study_design_scores_gemma":[0.00008940788,0.001187366,0.2005499,0.00003274391,0.00005309957,0.001920404,0.0003040846,0.002799738,0.7893847,0.001610216,0.002047436,0.000021004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950899,0.001757725,0.001120394,0.0001711831,0.00001391305,0.00001119657,0.00004170467,0.00001412947,0.001779986],"genre_scores_gemma":[0.9974227,0.00046516,0.0003859846,0.00003280339,0.000008972249,0.000004698699,0.00003428908,0.000004081191,0.001641349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001578649,"threshold_uncertainty_score":0.003146052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003005826500710775,"score_gpt":0.2196936610997872,"score_spread":0.2166878345990765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}