{"id":"W1967123560","doi":"10.1021/bi200960j","title":"Investigating the Molecular Determinants for Substrate Channeling in BphI–BphJ, an Aldolase–Dehydrogenase Complex from the Polychlorinated Biphenyls Degradation Pathway","year":2011,"lang":"en","type":"article","venue":"Biochemistry","topic":"Microbial bioremediation and biosurfactants","field":"Environmental Science","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Isobutyraldehyde; Propionaldehyde; Acetaldehyde; Chemistry; Aldolase A; Aldehyde; Aldehyde dehydrogenase; Cofactor; Stereochemistry; Glyceraldehyde; Aldehyde Reductase; Alcohol dehydrogenase; Dehydrogenase; Substrate (aquarium); Butyraldehyde; Enzyme; Biochemistry; Reductase; Catalysis; Ethanol; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002170882,0.0002308677,0.0001706958,0.00006132622,0.0001061253,0.0002663971,0.0002208067,0.0002894174,0.0003495554],"category_scores_gemma":[0.0003066255,0.0001244415,0.0001386733,0.0001095243,0.0002527782,0.0002912523,0.0001234618,0.0004223257,0.0001491912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003335111,"about_ca_system_score_gemma":0.0001710653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001218239,"about_ca_topic_score_gemma":0.0009388783,"domain_scores_codex":[0.9998568,0.00003114716,0.00001079112,0.00002098681,0.00005103803,0.00002913956],"domain_scores_gemma":[0.9998447,0.00005959763,0.00003602891,0.00001103156,0.00002369231,0.00002501335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008628933,0.00002709263,0.000222956,0.00001352044,0.000003008696,0.00003147668,0.00001536619,0.0000961637,0.9991161,0.00005744776,0.000006496639,0.0003241086],"study_design_scores_gemma":[0.00001330274,0.0001074951,0.002002347,0.000001309746,0.000006798304,0.0001101034,0.00001956897,0.001942574,0.9954848,0.00002604247,0.000281478,0.000004162693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983059,0.0001282087,0.001345808,0.00003260552,0.000003784538,0.000009912517,0.00003088513,0.000007729792,0.0001350915],"genre_scores_gemma":[0.998059,0.00007576939,0.00149453,0.00001355074,0.000001586297,0.000006071724,0.0000990171,0.00000662507,0.0002439041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218239,"threshold_uncertainty_score":0.002422333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05278180212795593,"score_gpt":0.2414509318874074,"score_spread":0.1886691297594515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}