{"id":"W1967140336","doi":"10.1159/000245059","title":"Vasopressin Type 2 Receptor V88M Mutation: Molecular Basis of Partial and Complete Nephrogenic Diabetes Insipidus","year":2009,"lang":"en","type":"article","venue":"Nephron Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Nephrogenic diabetes insipidus; Arginine vasopressin receptor 2; Vasopressin; Endocrinology; Internal medicine; Mutation; Receptor; Aquaporin 2; Mutant; Biology; Arginine; Diabetes insipidus; Medicine; Genetics; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004966808,0.0001355354,0.0001938047,0.00003419705,0.00004324502,0.000005295021,0.00008520126,0.0001620218,0.00005673555],"category_scores_gemma":[0.00001200044,0.000131988,0.00006694091,0.00008639404,0.0001196442,0.00000591282,0.00002043784,0.00005446883,0.000006799342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005041129,"about_ca_system_score_gemma":0.0000297548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003912393,"about_ca_topic_score_gemma":0.000001694964,"domain_scores_codex":[0.9992019,0.00005940791,0.0002026346,0.0002685424,0.00007653477,0.0001909838],"domain_scores_gemma":[0.9995492,0.000007653903,0.00009756404,0.000206683,0.00008829427,0.00005060293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001242865,0.00004179974,0.0001986652,0.00001458316,0.00004191947,6.17448e-7,0.00003858519,0.0001475658,0.9956823,0.0002464652,0.0003571298,0.003106071],"study_design_scores_gemma":[0.000611579,0.0007966986,0.03960003,0.00001002853,0.0000357568,0.000002500099,0.00002010035,0.0002390807,0.9467852,0.0006740185,0.01105307,0.0001720067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984207,0.0008412783,0.0001544478,0.0002000636,0.0001239233,0.0001136094,0.00001384998,0.00001195069,0.0001202474],"genre_scores_gemma":[0.9982993,0.00009167242,0.0003632839,0.0005527443,0.0002036304,0.000005024251,0.0004401763,0.00001175905,0.00003242984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04889718,"threshold_uncertainty_score":0.5382314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008131462261991799,"score_gpt":0.2226259090032357,"score_spread":0.2144944467412439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}