{"id":"W1967189220","doi":"10.1159/000149787","title":"Ile481 from the Guinea-Pig α-subunit Plays a Major Role in the Activation of ENaC by cpt-cAMP","year":2008,"lang":"en","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Université de Sherbrooke","keywords":"Epithelial sodium channel; Extracellular; Xenopus; Protein subunit; Cell biology; Biology; G alpha subunit; Chemistry; Endocrinology; Internal medicine; Biochemistry; Sodium; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001093719,0.0001561609,0.0001442256,0.00001174474,0.0001318802,0.000004763584,0.0002335769,0.0002669263,0.00004253028],"category_scores_gemma":[0.00002109111,0.0001036889,0.00007083763,0.00008602931,0.0002761034,0.000004722546,0.00003570324,0.0001420707,0.000003256629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005267812,"about_ca_system_score_gemma":0.000035542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008776217,"about_ca_topic_score_gemma":0.00001023899,"domain_scores_codex":[0.9991826,0.00006471543,0.0002033203,0.000285186,0.00009615689,0.0001680202],"domain_scores_gemma":[0.9994444,0.00003641926,0.0001070518,0.0003414346,0.00004226119,0.00002849677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001222147,0.00006496812,0.001726425,0.00001589063,0.00003030607,9.422537e-7,0.0003215518,0.000008304267,0.9959091,0.000007295269,0.00170507,0.00008792094],"study_design_scores_gemma":[0.000447158,0.00004380582,0.008929539,0.00001182224,0.0000160981,0.000006794683,0.0002360454,0.0000259769,0.9845271,0.0002142909,0.005414522,0.0001269005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997888,0.001369562,0.0001938948,0.0001853477,0.000035846,0.0001181642,0.00006145264,0.000005060624,0.0001427244],"genre_scores_gemma":[0.9961154,0.0002023562,0.0000300292,0.0002287058,0.0002607801,0.00002077997,0.00281367,0.0000104557,0.0003178253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01138206,"threshold_uncertainty_score":0.422831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008245220926959427,"score_gpt":0.1946112280237531,"score_spread":0.1863660070967937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}