{"id":"W1967190015","doi":"10.1152/ajpregu.00188.2005","title":"PKC and ERK are differentially involved in gonadotropin-releasing hormone-induced growth hormone gene expression in the goldfish pituitary","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Protein kinase C; Internal medicine; Endocrinology; Gonadotropin-releasing hormone; Biology; MAPK/ERK pathway; Signal transduction; Gene isoform; Gene expression; Hypothalamus; Secretion; Hormone; Calphostin C; Gonadotropic cell; Pituitary gland; Luteinizing hormone; Cell biology; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009259588,0.0002740131,0.0001608722,0.000254995,0.0001806389,0.0002259577,0.0001272881,0.0001945004,0.00103641],"category_scores_gemma":[0.00007808705,0.0001688444,0.0003598714,0.0001274002,0.0002528066,0.0003622069,0.0002375077,0.0003848246,0.0002505071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002601549,"about_ca_system_score_gemma":0.0002956229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007114653,"about_ca_topic_score_gemma":0.001296208,"domain_scores_codex":[0.9999174,0.0000043797,0.000007950529,0.0000255141,0.00002169291,0.00002303708],"domain_scores_gemma":[0.9999444,0.000004072299,0.00001672975,0.000005346834,0.00001103112,0.00001838038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004119248,0.00002916248,0.001668676,0.0001128822,0.000008837237,0.0001702317,0.00004265365,0.0000395201,0.9956639,0.0001656455,0.0000274285,0.001659189],"study_design_scores_gemma":[0.0002259439,0.0006168301,0.3166399,0.00004205286,0.0001173964,0.001954791,0.0005850044,0.001978675,0.6703625,0.0005417023,0.006901108,0.00003421741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963201,0.001346774,0.0008821642,0.0001106671,0.00004136606,0.00001956855,0.0001752015,0.00001332869,0.001090808],"genre_scores_gemma":[0.9896778,0.002282812,0.00186604,0.00008849493,0.00002329554,0.00005114977,0.0004809622,0.000007400373,0.005522092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00103641,"threshold_uncertainty_score":0.003467143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0256216852127927,"score_gpt":0.271551324904235,"score_spread":0.2459296396914423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}