{"id":"W1967238137","doi":"10.1158/0008-5472.sabcs11-pd06-01","title":"PD06-01: Molecular Classification with 21 Gene Assay (Oncotype DX®) Shows in 196,967 ER Positive Patients High Frequency of Low Recurrence Score [LRS] in Both Node Positive (N+) and Negative (N-) Breast Cancer (BrCa) Cohorts. Definition of Chemoresistance Based on LRS with Cost and Guideline Implications.","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Toronto; BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Oncology; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004530844,0.0001669771,0.0002255015,0.0007840851,0.0001431203,0.0003919669,0.0003771526,0.0001848293,0.002076207],"category_scores_gemma":[0.001281722,0.0001155997,0.000171681,0.001120467,0.0001784661,0.0001945089,0.0004203419,0.0002337112,0.0004890661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00027404,"about_ca_system_score_gemma":0.0002670832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002124654,"about_ca_topic_score_gemma":0.003952614,"domain_scores_codex":[0.9995832,0.00008836681,0.00006743705,0.0001044224,0.0001155623,0.00004105744],"domain_scores_gemma":[0.9989936,0.0001455732,0.0006290645,0.00006601432,0.0000792471,0.00008665494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003499562,0.00002061174,0.9929281,0.00002309696,0.00002055419,0.00004385817,0.000009365198,0.0001424095,0.0005540706,0.00002920854,0.00104232,0.004836436],"study_design_scores_gemma":[0.00002450157,0.0001153517,0.9969845,0.000004758946,0.00001849359,0.0005026399,0.00002661122,0.0003726519,0.0008159599,0.00001909832,0.001112838,0.000002620464],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846029,0.0002827877,0.0004232273,0.00008604532,0.00001192176,0.00005095771,0.01260775,0.00002193031,0.001912467],"genre_scores_gemma":[0.9820202,0.0001625989,0.001204834,0.00004654261,0.00001203385,0.00004825415,0.0157026,0.000006661764,0.0007961542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002124654,"threshold_uncertainty_score":0.00694561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03673700520553955,"score_gpt":0.3121608027012461,"score_spread":0.2754237974957065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}