{"id":"W1967421034","doi":"10.1016/s0006-2952(00)00444-5","title":"Integrin-linked kinase (ILK): a “hot” therapeutic target","year":2000,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; University of British Columbia; Celator Pharmaceuticals (Canada)","funders":"","keywords":"Integrin-linked kinase; Kinase; Integrin; Cell biology; Chemistry; Computational biology; Cancer research; Biology; Protein kinase A; Biochemistry; Cyclin-dependent kinase 2; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002788498,0.0007432402,0.002500568,0.0004546679,0.00006377518,0.00002105086,0.0006463465,0.001178007,0.01984309],"category_scores_gemma":[0.00009272943,0.000567932,0.001037794,0.0006716674,0.0004290651,0.00002215292,0.0002878085,0.002463968,0.003192564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004856886,"about_ca_system_score_gemma":0.001008266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008061512,"about_ca_topic_score_gemma":4.601829e-8,"domain_scores_codex":[0.9961348,0.0004391944,0.0009192678,0.001045883,0.0005118589,0.0009490452],"domain_scores_gemma":[0.997936,0.0004353219,0.0001942919,0.0005974395,0.0001232765,0.0007136583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004973885,0.0007923001,5.264657e-7,0.01082901,0.0007490845,0.0009935203,0.00001430633,6.325612e-8,0.02304505,0.00001256553,0.3672886,0.5957775],"study_design_scores_gemma":[0.001314709,0.0002686701,8.951223e-7,0.001473545,0.001769653,0.0004091567,0.000002565106,0.00002230096,0.005622521,0.00003053505,0.9886235,0.000461935],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001776598,0.9933842,0.00001299465,0.000330725,0.0004552039,0.002086741,0.00004961662,0.0001622805,0.003340611],"genre_scores_gemma":[0.0001133933,0.9904737,0.0003456378,0.001800812,0.001086475,0.000464418,0.0006134916,0.0001662338,0.004935812],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6213349,"threshold_uncertainty_score":0.9998374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07812614595187779,"score_gpt":0.4272002769954527,"score_spread":0.3490741310435749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}