{"id":"W1967456673","doi":"10.1371/journal.pone.0005722","title":"Molecular Signatures of Prostate Stem Cells Reveal Novel Signaling Pathways and Provide Insights into Prostate Cancer","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health; School of Medicine, New York University; York University; Memorial Sloan-Kettering Cancer Center; Amgen","keywords":"Stem cell; Biology; Prostate; Prostate cancer; Cancer stem cell; Wnt signaling pathway; Cancer research; Carcinogenesis; Progenitor cell; Population; Cell biology; Cancer; Signal transduction; Genetics; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001299397,0.0002281823,0.0004794178,0.0001589689,0.00008284597,0.00002842564,0.00008694099,0.0001069445,0.000009540849],"category_scores_gemma":[0.00001698768,0.0001702325,0.00005745472,0.0002605194,0.0001175321,0.0001235379,0.00004792701,0.0002941833,0.000002790322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001212722,"about_ca_system_score_gemma":0.0002907366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007444045,"about_ca_topic_score_gemma":0.000007106109,"domain_scores_codex":[0.9982477,0.00003923957,0.0003316255,0.0004057384,0.0006119491,0.0003637589],"domain_scores_gemma":[0.9990488,0.00004048607,0.000135043,0.0002461187,0.0003126276,0.0002169519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009046489,0.001340685,0.001760685,0.001085106,0.0003189984,0.000115152,0.003492264,0.00003383029,0.9856464,0.00007882129,0.00004261256,0.005180805],"study_design_scores_gemma":[0.002804963,0.001359101,0.001076997,0.001502379,0.0002468763,0.00000159347,0.0001582121,0.0002758239,0.9919348,0.0003821688,0.00007295134,0.0001841821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825654,0.0141884,0.00001044603,0.001076889,0.00001926612,0.001826676,0.00003691756,0.00005716137,0.000218853],"genre_scores_gemma":[0.9954678,0.001594181,0.001494477,0.000284007,0.0000621558,0.0001157365,0.00002544172,0.00003271196,0.0009234819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01290241,"threshold_uncertainty_score":0.6941882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0361791619269138,"score_gpt":0.2659839534712455,"score_spread":0.2298047915443317,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}