{"id":"W1967477962","doi":"10.1371/journal.pmed.0030094","title":"Enrolling Women into HIV Preventive Vaccine Trials: An Ethical Imperative but a Logistical Challenge","year":2006,"lang":"en","type":"article","venue":"PLoS Medicine","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; McMaster University","funders":"Ontario HIV Treatment Network","keywords":"HIV vaccine; Human immunodeficiency virus (HIV); Medicine; AIDS Vaccines; Pre-exposure prophylaxis; Clinical trial; Family medicine; Alternative medicine; Virology; Environmental health; Vaccine trial; Men who have sex with men; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2344082,0.0006360151,0.002126305,0.0008772718,0.004139414,0.007781482,0.003303703,0.02259226,0.003898676],"category_scores_gemma":[0.2641709,0.0007724635,0.001257047,0.0009799831,0.01352858,0.008259524,0.006176671,0.02509045,0.001875045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002799284,"about_ca_system_score_gemma":0.01989826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001348066,"about_ca_topic_score_gemma":0.003408208,"domain_scores_codex":[0.808203,0.1628706,0.008823849,0.003653986,0.01337395,0.003074542],"domain_scores_gemma":[0.4596466,0.4748768,0.01647689,0.01423146,0.0175009,0.01726739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001992188,0.00124254,0.01608054,0.002253469,0.0004267118,0.002901541,0.02471025,0.001158752,0.004840411,0.3083037,0.4029513,0.2331386],"study_design_scores_gemma":[0.001962763,0.002997878,0.008476511,0.004681812,0.0002893522,0.005556077,0.01524781,0.003433769,0.004100286,0.2986396,0.6542951,0.0003189696],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.004314796,0.002044202,0.01262769,0.9734763,0.003847506,0.000375488,0.0000242395,0.00003180042,0.003257908],"genre_scores_gemma":[0.07561196,0.003119364,0.03697111,0.8680492,0.009298536,0.002705476,0.00004026345,0.00004970611,0.004154427],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.2344082,"threshold_uncertainty_score":0.944111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4710769144362194,"score_gpt":0.573731512867316,"score_spread":0.1026545984310967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}