{"id":"W1967505760","doi":"10.1016/j.ajhg.2013.03.004","title":"Complete Haplotype Sequence of the Human Immunoglobulin Heavy-Chain Variable, Diversity, and Joining Genes and Characterization of Allelic and Copy-Number Variation","year":2013,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Simon Fraser University","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; Howard Hughes Medical Institute","keywords":"Haplotype; Genetics; Allele; Biology; Gene; Sequence (biology); Copy-number variation; Immunoglobulin heavy chain; Computational biology; Evolutionary biology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002007836,0.00008503223,0.0001760571,0.00002224497,0.0003050812,0.00002062818,0.000156458,0.00002661005,0.00001177243],"category_scores_gemma":[0.000008578468,0.00005973645,0.00002836566,0.00005457624,0.000350712,0.00000875671,0.0003651957,0.00005997859,1.431682e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006253359,"about_ca_system_score_gemma":0.00002435112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001977611,"about_ca_topic_score_gemma":0.000005657823,"domain_scores_codex":[0.9993281,0.0001170198,0.0002837947,0.00008438519,0.0001008035,0.0000859268],"domain_scores_gemma":[0.9990374,0.00001537319,0.0005970335,0.0001474085,0.0001726224,0.00003017635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001572051,0.000014197,0.08307396,0.00001453385,0.00006849093,1.335635e-7,0.001041975,0.00004240606,0.9149554,0.0003075924,0.000005529289,0.000460053],"study_design_scores_gemma":[0.0004918117,0.0008234415,0.9588368,0.00004562092,0.0001200821,0.0001219602,0.0007774701,0.0001520625,0.03700152,0.001320606,0.0001644058,0.0001442032],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990351,0.0002607697,0.0004338515,0.0001086817,0.00002684407,0.00008864526,0.00002138707,0.000001023241,0.00002370792],"genre_scores_gemma":[0.9984932,0.0005079757,0.0007990131,0.00009116843,0.00005554831,9.939338e-7,0.000008450648,0.000007651788,0.00003602506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8779539,"threshold_uncertainty_score":0.2435981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01669984815357575,"score_gpt":0.2288724924812086,"score_spread":0.2121726443276328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}