{"id":"W1967520716","doi":"10.1039/c2an36564b","title":"A novel colorimetric potassium sensor based on the substitution of lead from G-quadruplex","year":2012,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Fundamental Research Funds for the Central Universities; Natural Sciences and Engineering Research Council of Canada","keywords":"Deoxyribozyme; G-quadruplex; Hemin; Chemistry; Detection limit; ABTS; DNA; Aptamer; Potassium; Combinatorial chemistry; Catalysis; Colorimetry; Biochemistry; Chromatography; Molecular biology; Heme; Enzyme; Antioxidant; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002206912,0.0007126371,0.0006658245,0.0003655252,0.0002532783,0.0005190228,0.001122526,0.001065284,0.0006860145],"category_scores_gemma":[0.0003308324,0.0003633442,0.0002915326,0.0003631626,0.000437817,0.0007905139,0.0005476716,0.0006189915,0.0006454305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004238486,"about_ca_system_score_gemma":0.0003059046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002756463,"about_ca_topic_score_gemma":0.0005632774,"domain_scores_codex":[0.9994202,0.00007554529,0.00003535816,0.0002073289,0.0002037938,0.00005776162],"domain_scores_gemma":[0.9998401,0.00002806313,0.00004600814,0.00001177665,0.00004035283,0.0000335684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005162812,0.0000142505,0.00009825984,0.0000753812,0.000005815042,0.00004442747,0.0000151867,0.00005659386,0.9964299,0.0001008427,0.0001105809,0.002997116],"study_design_scores_gemma":[0.00001073651,0.0002084954,0.0003059561,0.000003433812,0.00001142258,0.000350404,0.000008866376,0.001296852,0.9958801,0.00004116924,0.001869686,0.00001292473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7574022,0.009087299,0.219211,0.0007860792,0.0006739175,0.0003964177,0.00111585,0.005487495,0.005839745],"genre_scores_gemma":[0.8696511,0.00261207,0.1187867,0.0006399656,0.000072659,0.0001610907,0.0006618369,0.0001538939,0.007260764],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001122526,"threshold_uncertainty_score":0.003075242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0240256986616905,"score_gpt":0.2716688303312164,"score_spread":0.2476431316695259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}