{"id":"W1967545780","doi":"10.1128/iai.05478-11","title":"The Deubiquitinase Activity of the Salmonella Pathogenicity Island 2 Effector, SseL, Prevents Accumulation of Cellular Lipid Droplets","year":2011,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Victoria; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Effector; Biology; Secretion; Pathogenicity island; Salmonella; Salmonella enterica; Cell biology; Microbiology; Bacteria; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000215035,0.00008754393,0.00009273144,0.00001290075,0.0001826332,0.000007710699,0.00008653318,0.00007419493,0.00001137957],"category_scores_gemma":[0.0001371215,0.00005518715,0.00009455896,0.00005744625,0.0001376629,0.00000609146,0.0001151128,0.00008237475,5.429545e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005089973,"about_ca_system_score_gemma":0.00002691612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000636508,"about_ca_topic_score_gemma":0.0001453811,"domain_scores_codex":[0.9992951,0.0002865092,0.0001434405,0.0001046304,0.00007747956,0.00009283728],"domain_scores_gemma":[0.9993855,0.00003396354,0.0001652754,0.0003175042,0.0000634664,0.00003430768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001721552,0.0001731202,0.1261221,0.00004904785,0.00003517617,1.740557e-7,0.00008360608,0.000008526585,0.870957,0.00002850769,0.00003869429,0.002331979],"study_design_scores_gemma":[0.0002871883,0.0001223463,0.3351945,0.00001368463,0.00002618564,0.000002276381,0.00001090794,0.00007004981,0.6639208,0.00004643206,0.0002571997,0.00004846315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998415,0.0001869744,0.000463386,0.000005076788,0.000143482,0.000187439,0.00002354245,0.000003890423,0.000571236],"genre_scores_gemma":[0.9995718,0.0003134099,0.000006967779,0.000009141795,0.00002618541,0.000009014771,0.00001168338,0.00000606057,0.0000457381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2090724,"threshold_uncertainty_score":0.2250467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02293750438407776,"score_gpt":0.2634619933456585,"score_spread":0.2405244889615807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}