{"id":"W1967545780","doi":"10.1128/iai.05478-11","title":"The Deubiquitinase Activity of the Salmonella Pathogenicity Island 2 Effector, SseL, Prevents Accumulation of Cellular Lipid Droplets","year":2011,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Victoria; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Effector; Biology; Secretion; Pathogenicity island; Salmonella; Salmonella enterica; Cell biology; Microbiology; Bacteria; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001535472,0.0002523448,0.0001817301,0.0001469852,0.00007847777,0.0002382637,0.0001341474,0.0001822467,0.0005807849],"category_scores_gemma":[0.0001232609,0.0001350054,0.0001494902,0.00009057944,0.0002054762,0.000139631,0.0001562353,0.0002422088,0.0001600536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001712275,"about_ca_system_score_gemma":0.0001636236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002263927,"about_ca_topic_score_gemma":0.000584551,"domain_scores_codex":[0.9999155,0.00002044028,0.00001101705,0.00001439868,0.00001685611,0.00002193776],"domain_scores_gemma":[0.9998918,0.00001600864,0.00003746977,0.00001837248,0.000008210412,0.00002820246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001108218,0.00002079418,0.0001798762,0.00001380013,0.000002671287,0.00002284486,0.00000377259,0.00002996833,0.9991711,0.00002715185,0.000007313239,0.0004099567],"study_design_scores_gemma":[0.00001067175,0.0002341133,0.001763253,0.000002028752,0.000005125529,0.00009906488,0.00001008879,0.0003116693,0.9971123,0.00001502091,0.0004354486,0.000001304368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99871,0.0003104187,0.0006245313,0.00002199751,0.00000708222,0.000003799526,0.00004128815,0.00001786014,0.0002630269],"genre_scores_gemma":[0.9980791,0.0002127136,0.0005944784,0.00001158811,0.00000246453,0.000004731488,0.0001346498,0.000007026887,0.0009532445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005807849,"threshold_uncertainty_score":0.001942933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02293750438407776,"score_gpt":0.2634619933456585,"score_spread":0.2405244889615807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}