{"id":"W1967555288","doi":"10.1111/j.1399-0004.2010.01414_2.x","title":"Genetic variants associated with cisplatin‐induced hearing loss","year":2010,"lang":"en","type":"letter","venue":"Clinical Genetics","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute","funders":"","keywords":"Hearing loss; Cisplatin; Genetics; Ototoxicity; Thiopurine methyltransferase; Chemotherapy; Audiology; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0004292619,0.0005688026,0.0006704951,0.00006014965,0.0001287369,0.0000928771,0.000679955,0.004697275,0.00007985055],"category_scores_gemma":[0.0001794271,0.0005233037,0.0003370937,0.0001276519,0.0002224426,0.000001627692,0.0002884738,0.003515955,0.00003670201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002741462,"about_ca_system_score_gemma":0.0004761738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001276362,"about_ca_topic_score_gemma":0.0001191574,"domain_scores_codex":[0.99663,0.0002107411,0.0008444302,0.00113413,0.000434894,0.000745777],"domain_scores_gemma":[0.9975814,0.0001195393,0.0005011836,0.001314022,0.0002768974,0.0002069388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006294755,0.0009716543,0.01431154,0.0002614094,0.004794119,0.001805106,0.0001133672,0.0001445727,0.2868221,0.00003326605,0.613079,0.07703434],"study_design_scores_gemma":[0.00229395,0.002631873,0.0108682,0.0001366861,0.000540394,0.00008980496,0.00000416867,0.0001762526,0.01174538,0.0004779136,0.9696655,0.001369825],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9476957,0.001145638,0.003060763,0.04005373,0.005115207,0.001154184,0.0002866508,0.00008905301,0.001399056],"genre_scores_gemma":[0.3355886,0.001986551,0.005928131,0.628,0.02010846,0.0001056953,0.001587616,0.0005870985,0.00610781],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6121071,"threshold_uncertainty_score":0.9997218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06230607066634578,"score_gpt":0.33521865335874,"score_spread":0.2729125826923942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}