{"id":"W1967662525","doi":"10.1016/j.stem.2012.02.007","title":"Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs","year":2012,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":323,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"BC Cancer Agency; Canadian Institutes of Health Research; Wellcome Trust","keywords":"Biology; Haematopoiesis; Stem cell; Myeloid; Progenitor cell; Bone marrow; Lymphopoiesis; Cell biology; Immunology; Hematopoietic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003617461,0.0006562073,0.0007823396,0.0001687082,0.0003103431,0.0001139709,0.000207653,0.0002844574,0.0001363708],"category_scores_gemma":[0.000001660533,0.0005657085,0.0001641574,0.0002580019,0.0001367132,0.0001953628,0.0001225391,0.0002773023,0.0003836278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002160891,"about_ca_system_score_gemma":0.0001568735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001540027,"about_ca_topic_score_gemma":0.00001053572,"domain_scores_codex":[0.9963769,0.000125848,0.000905898,0.0007289487,0.0007216677,0.001140793],"domain_scores_gemma":[0.9980435,0.0001543994,0.0002930999,0.0005925712,0.00008805947,0.0008284017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000688988,0.004027744,0.7149853,0.03214968,0.0001820723,0.0003719029,0.04490643,0.000004721075,0.191277,0.00008428885,0.0001544126,0.01116751],"study_design_scores_gemma":[0.005680366,0.0002305907,0.1081107,0.0008199407,0.0005950739,0.0004112882,0.00311864,0.00005853754,0.8778589,0.00000647044,0.002092856,0.001016604],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852876,0.003408884,0.0008999523,0.0000297804,0.0005576276,0.001337399,0.000008125222,0.0002214334,0.008249194],"genre_scores_gemma":[0.9854172,0.0001451242,0.0009355262,0.00003279859,0.0001666748,0.000155657,0.00009758662,0.0001380694,0.01291134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6865819,"threshold_uncertainty_score":0.9996794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01618033210429273,"score_gpt":0.224969724147561,"score_spread":0.2087893920432682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}