{"id":"W1967707100","doi":"10.3389/fgene.2014.00161","title":"Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders","year":2014,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Epigenetics; DNA methylation; Epigenomics; Biology; Histone; Genetics; Phenotype; Genomic imprinting; microRNA; Fetal alcohol syndrome; Bioinformatics; Neuroscience; Gene expression; Gene; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002740366,0.0004581703,0.0006400247,0.0005442636,0.0002070485,0.0005393015,0.0005819105,0.0006588217,0.001124453],"category_scores_gemma":[0.0001592619,0.0001296199,0.0004180043,0.0004186732,0.0007096626,0.0006295834,0.0004185446,0.001251502,0.000335737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000555985,"about_ca_system_score_gemma":0.0005226341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00111263,"about_ca_topic_score_gemma":0.001661684,"domain_scores_codex":[0.9998956,0.00002725544,0.000008488409,0.00002897989,0.00002334766,0.00001633985],"domain_scores_gemma":[0.9999214,0.00002281706,0.00001843804,0.000007989706,0.00001454854,0.00001469776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001197045,0.0004179337,0.008684418,0.01219615,0.0006089988,0.006199782,0.00126293,0.002001099,0.5049951,0.1001848,0.02313101,0.3391208],"study_design_scores_gemma":[0.0001004512,0.002308965,0.04384955,0.003188525,0.001169307,0.01663393,0.001502288,0.003082292,0.1039159,0.06352694,0.7605502,0.000171502],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07498772,0.8768082,0.0225887,0.008497999,0.001695173,0.00009531403,0.0008811481,0.0002843631,0.01416137],"genre_scores_gemma":[0.1753157,0.8074138,0.007014774,0.002029134,0.0004963581,0.0001697095,0.000511135,0.0000271026,0.007022264],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001124453,"threshold_uncertainty_score":0.004034042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02446392898416145,"score_gpt":0.3021244322958492,"score_spread":0.2776605033116878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}