{"id":"W1967743782","doi":"10.1021/ic5028948","title":"Biotransformations of Antidiabetic Vanadium Prodrugs in Mammalian Cells and Cell Culture Media: A XANES Spectroscopic Study","year":2015,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Vanadium and Halogenation Chemistry","field":"Chemistry","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biological and Environmental Research; National Center for Research Resources; Australian Research Council; Australian Synchrotron; Alzheimer Society Research Program; National Institutes of Health; U.S. Department of Energy","keywords":"Chemistry; Vanadium; Cell culture; XANES; Prodrug; A549 cell; Vanadate; Cytoplasm; Stereochemistry; Cell; Biochemistry; Biophysics; Spectroscopy; Organic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001502705,0.0002670423,0.0003480744,0.00004491615,0.00004910331,0.00003461001,0.0003010042,0.0002479683,0.0006934216],"category_scores_gemma":[0.00006643804,0.0002731952,0.000048396,0.0002932018,0.0001101355,0.000107719,0.00006356746,0.0003444755,0.00002124479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001440437,"about_ca_system_score_gemma":0.0002589599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001780207,"about_ca_topic_score_gemma":0.0001260649,"domain_scores_codex":[0.9984424,0.00001290183,0.0005073886,0.0003813775,0.0003134317,0.0003425247],"domain_scores_gemma":[0.999014,0.00003347435,0.0001591073,0.0003928945,0.0001232019,0.0002773055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001028926,0.0003763102,0.0154296,0.0007344038,0.00001840848,0.00002307659,0.005244936,0.000002922257,0.9774919,0.000002004925,0.0006422573,0.00002390032],"study_design_scores_gemma":[0.001730762,0.00001788883,0.00052564,0.00004924866,0.00004951534,0.00001740973,0.009983872,0.00001773941,0.9867369,0.00008438723,0.0005230284,0.0002636222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834716,0.000501546,0.000001943676,0.0001209948,0.00006432599,0.0001247745,0.00008104452,0.000050208,0.01558359],"genre_scores_gemma":[0.9974998,0.00004371744,0.0000902696,0.00001669189,0.0001236058,0.00001700541,0.00006920462,0.0000279404,0.00211178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01490396,"threshold_uncertainty_score":0.999972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009737420020852237,"score_gpt":0.2154664223674817,"score_spread":0.2057290023466294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}