{"id":"W1967774193","doi":"10.1016/j.hrthm.2005.04.026","title":"Specific potassium channel blockade for arrhythmia prevention in the ionically remodeled failing heart: Peril or panacea?","year":2005,"lang":"en","type":"letter","venue":"Heart Rhythm","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Torsades de pointes; Medicine; Heart failure; Afterdepolarization; Cardiology; hERG; Internal medicine; Proarrhythmia; Repolarization; Blockade; QT interval; Potassium channel; Electrophysiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001310535,0.0005220011,0.002127338,0.0003381844,0.001222252,0.001614369,0.00107825,0.02146553,0.006136158],"category_scores_gemma":[0.007227462,0.0002439363,0.0009369839,0.0003197647,0.001673391,0.002699675,0.0006025623,0.0158796,0.003159916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001151699,"about_ca_system_score_gemma":0.001041476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007580406,"about_ca_topic_score_gemma":0.002584464,"domain_scores_codex":[0.9992442,0.0002629882,0.0001124099,0.00009173619,0.0001618725,0.0001267101],"domain_scores_gemma":[0.9978395,0.001328329,0.0001446465,0.00006520186,0.0002291901,0.0003931551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001437134,0.0003348338,0.005754959,0.0004822591,0.0001674839,0.02598076,0.0002375978,0.0006158216,0.001550904,0.01210408,0.817533,0.1338012],"study_design_scores_gemma":[0.002248205,0.00138575,0.00908578,0.001721033,0.0002724962,0.04877178,0.001507475,0.003532389,0.001526879,0.06003474,0.8696928,0.0002206211],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002826921,0.00846451,0.0005114269,0.973636,0.008786039,0.00001516215,0.00005026662,0.0000458168,0.00566389],"genre_scores_gemma":[0.04715224,0.01673549,0.001633148,0.8073032,0.1159334,0.00007536037,0.00008189066,0.00003532258,0.0110499],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02146553,"threshold_uncertainty_score":0.02052748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03365632254280244,"score_gpt":0.2971425047113986,"score_spread":0.2634861821685962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}