{"id":"W1967782236","doi":"10.1021/nn504186b","title":"Modulation of Complement Activation and Amplification on Nanoparticle Surfaces by Glycopolymer Conformation and Chemistry","year":2014,"lang":"en","type":"article","venue":"ACS Nano","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glycopolymer; Complement system; Chemistry; Biophysics; Polymer; Chemical engineering; Materials science; Organic chemistry; Polymerization; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001262097,0.00006924714,0.00009841376,0.00002069385,0.00008172438,0.000007687556,0.00003913155,0.00004244438,0.00009653239],"category_scores_gemma":[0.0000359262,0.00006561552,0.000008933956,0.00003657172,0.00005834421,0.0000967681,0.0000228804,0.00002410141,0.00001147149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001429959,"about_ca_system_score_gemma":0.000005669206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004545248,"about_ca_topic_score_gemma":0.000001339847,"domain_scores_codex":[0.9995007,0.00005449646,0.0002052494,0.0001177328,0.00003534338,0.00008648769],"domain_scores_gemma":[0.9995839,0.00009001242,0.0001516368,0.0001244578,0.00003860855,0.00001141154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000465331,0.00003926759,0.004785991,0.00004004062,0.00001698824,3.598231e-9,0.0001202001,0.000010836,0.9889392,0.0006843936,0.001031681,0.004284925],"study_design_scores_gemma":[0.0007239725,0.00006737573,0.03201338,0.00002823175,0.00001097824,9.373766e-7,0.0001251876,0.0002097921,0.9630692,0.0001039577,0.003581209,0.00006577665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987818,0.0001908049,0.0003138534,0.0001564941,0.00003577255,0.0001735751,0.00002918924,0.00001971814,0.0002988073],"genre_scores_gemma":[0.9995213,0.00001396485,0.00001591831,0.00003568561,0.000004967037,0.00001337602,0.0002932268,0.000004016475,0.00009758684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02722739,"threshold_uncertainty_score":0.2675723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01161610172947097,"score_gpt":0.2357792157070202,"score_spread":0.2241631139775492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}