{"id":"W1967792499","doi":"10.1056/nejmoa1406470","title":"Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer","year":2015,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":2071,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenvatinib; Medicine; Refractory (planetary science); Thyroid cancer; Fibroblast growth factor receptor; Receptor; Internal medicine; Thyroid; Placebo; Vascular endothelial growth factor; Endocrinology; Oncology; Cancer research; Fibroblast growth factor; VEGF receptors; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271525,0.0007456121,0.002241574,0.0004649369,0.0002855335,0.0007070859,0.0005130549,0.001003635,0.003643526],"category_scores_gemma":[0.001541895,0.0002863682,0.001028606,0.0003484675,0.0005633504,0.0006509741,0.0003114135,0.001649414,0.000413402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008837559,"about_ca_system_score_gemma":0.0008033947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004569889,"about_ca_topic_score_gemma":0.001155089,"domain_scores_codex":[0.9993968,0.0003518343,0.00005046788,0.00007857157,0.00005176604,0.00007050105],"domain_scores_gemma":[0.9994094,0.0002105874,0.0001524003,0.00002367384,0.00002946923,0.0001744617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9215647,0.004709545,0.0007452044,0.0008313823,0.0009311862,0.00007497297,0.00006171287,0.0006183343,0.006909474,0.00014072,0.0009464467,0.06246632],"study_design_scores_gemma":[0.7437033,0.2440229,0.004958588,0.0001401173,0.0009651611,0.0001692175,0.00006202942,0.001163329,0.001912761,0.0003856806,0.002493624,0.00002323926],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741192,0.02034642,0.000308172,0.000795107,0.0005564957,0.0009453743,0.000413559,0.00009592581,0.002419742],"genre_scores_gemma":[0.9917663,0.00464174,0.0004039082,0.0006180606,0.0003248181,0.0008171279,0.000306297,0.00001041856,0.001111451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003643526,"threshold_uncertainty_score":0.01218879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06912991086914029,"score_gpt":0.3433677123675156,"score_spread":0.2742378014983753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}