{"id":"W1967801015","doi":"10.1158/1538-7445.am2012-4103","title":"Abstract 4103: Hepatocellular carcinoma-specific isoforms of methylated DNA-binding protein 2 and their therapeutic and diagnostic potential","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"DNA methylation; Hepatocellular carcinoma; Cancer research; Gene knockdown; Metastasis; Biology; Cancer; Liver cancer; Cancer cell; Liver cell; Gene isoform; Somatic cell; Cell culture; Gene; Medicine; Internal medicine; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707226,0.0002933309,0.0002030168,0.0001936663,0.0001469841,0.0002247352,0.0002080987,0.0003553881,0.002694199],"category_scores_gemma":[0.0000926669,0.00008693735,0.000231769,0.0002353202,0.0001341904,0.0001309197,0.0001196752,0.0006436218,0.0008872616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003533704,"about_ca_system_score_gemma":0.0002519752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006069379,"about_ca_topic_score_gemma":0.0005391617,"domain_scores_codex":[0.9999287,0.00001097495,0.000004548936,0.00001260373,0.0000279905,0.00001511654],"domain_scores_gemma":[0.9999624,0.000004972369,0.000008682021,0.000003057556,0.00000875524,0.0000121593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003575582,0.00009240073,0.0005258628,0.0001069665,0.00001329246,0.0001232926,0.000008936517,0.00008114168,0.9912832,0.0002183554,0.0009005752,0.006288408],"study_design_scores_gemma":[0.000120384,0.001358646,0.008646858,0.00002117912,0.00007495265,0.002291399,0.00003624622,0.001481789,0.9565853,0.0002591778,0.02910808,0.000016078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9329419,0.0430215,0.00804421,0.001746042,0.0006172355,0.0001792784,0.002651315,0.0003236991,0.01047476],"genre_scores_gemma":[0.966722,0.007970718,0.004918318,0.00048665,0.000111768,0.0001219578,0.005126886,0.00004133512,0.01450035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002694199,"threshold_uncertainty_score":0.009012938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05481077527530728,"score_gpt":0.3275848451606018,"score_spread":0.2727740698852946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}