{"id":"W1967851866","doi":"10.1210/endo.142.7.8229","title":"L-Type Ca2+ Channel Regulation by Pituitary Adenylate Cyclase-Activating Polypeptide in Vascular Myocytes from Spontaneously Hypertensive Rats*","year":2001,"lang":"en","type":"article","venue":"Endocrinology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Internal medicine; Endocrinology; Protein kinase C; Vascular smooth muscle; Calphostin C; Pituitary adenylate cyclase-activating peptide; Chemistry; Forskolin; Activator (genetics); Protein kinase A; Stimulation; Vasoactive intestinal peptide; Biology; Medicine; Signal transduction; Receptor; Phosphorylation; Neuropeptide; Smooth muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148696,0.0002392638,0.0004015044,0.0002684463,0.0002436088,0.0002104209,0.00016311,0.0002544112,0.001215035],"category_scores_gemma":[0.0001824762,0.0002016368,0.0004099126,0.0001756176,0.0002414139,0.0003010021,0.0002070118,0.0008741511,0.0002474071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001986288,"about_ca_system_score_gemma":0.0001571069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001999066,"about_ca_topic_score_gemma":0.002299811,"domain_scores_codex":[0.999892,0.000008758873,0.00001184782,0.00002290945,0.00003117875,0.00003330508],"domain_scores_gemma":[0.9998366,0.00001902537,0.00003571301,0.00001938974,0.00002487731,0.00006436096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002556068,0.00002789982,0.0007666248,0.00002590591,0.000007636031,0.0001413514,0.00004689684,0.00001194455,0.9978247,0.00002770206,0.00003331715,0.0008304712],"study_design_scores_gemma":[0.0001410343,0.002161454,0.3023341,0.00001901323,0.0001916767,0.001486904,0.0005468435,0.001784053,0.687597,0.0002207763,0.003480538,0.00003660105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974988,0.000819646,0.0007342783,0.0001147339,0.00005173158,0.00001036334,0.0002024091,0.0000245821,0.0005434331],"genre_scores_gemma":[0.9949706,0.001308011,0.00116408,0.0001025867,0.00007470392,0.00006303234,0.0006069895,0.00002015188,0.001689827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001999066,"threshold_uncertainty_score":0.004064739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02577434332234476,"score_gpt":0.2401799013164553,"score_spread":0.2144055579941105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}