{"id":"W1967874261","doi":"10.1021/ac701604a","title":"Capillary Electrophoresis Frontal Analysis for Characterization of α<sub>v</sub>β<sub>3</sub> Integrin Binding Interactions","year":2008,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Centre for Drug Research and Development","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Università degli Studi di Pavia","keywords":"Chemistry; Capillary electrophoresis; Pentapeptide repeat; Aspartic acid; Affinity electrophoresis; Binding constant; Alanine; Binding site; Ligand (biochemistry); Arginine; Peptide; Integrin; Chromatography; Amino acid; Biochemistry; Affinity chromatography; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005597979,0.0007842085,0.0005414934,0.00089596,0.0005183998,0.0005280041,0.0005986072,0.0005417513,0.002562333],"category_scores_gemma":[0.001100171,0.0002204409,0.0002930706,0.0006144951,0.0003737187,0.0005370138,0.0002739867,0.0007553955,0.0007842952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005375622,"about_ca_system_score_gemma":0.0006220277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00285972,"about_ca_topic_score_gemma":0.003096054,"domain_scores_codex":[0.9995854,0.00007016172,0.00001643849,0.0001131674,0.0001623886,0.00005240252],"domain_scores_gemma":[0.9992175,0.0003472404,0.00006204506,0.00004427957,0.0002810344,0.00004794973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009890431,0.00007133771,0.0005898465,0.0001068934,0.00001847588,0.00007447535,0.00004732989,0.0002108386,0.9764529,0.00179464,0.0004171082,0.02011729],"study_design_scores_gemma":[0.0000146083,0.0002148044,0.00453613,0.00001557964,0.00004193225,0.0008032379,0.00006487827,0.01938628,0.9695421,0.00073167,0.004614613,0.00003419503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2775008,0.006374093,0.7040426,0.0003404071,0.0001688639,0.0002851005,0.001025872,0.002679052,0.007583234],"genre_scores_gemma":[0.4901468,0.00722756,0.4946195,0.0003122233,0.00009289305,0.0006629666,0.001416319,0.0002201289,0.005301621],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00285972,"threshold_uncertainty_score":0.008571923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02075208774601022,"score_gpt":0.2798333767611167,"score_spread":0.2590812890151065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}