{"id":"W1967888916","doi":"10.4161/mabs.36336","title":"Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV","year":2014,"lang":"en","type":"article","venue":"mAbs","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Glycosylation; Recombinant DNA; Monoclonal antibody; Nicotiana benthamiana; Antibody; Glycan; Biology; Transgene; Microbiology; Virology; Glycoprotein; Chemistry; Molecular biology; Virus; Biochemistry; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001393485,0.0003053093,0.0001725673,0.0001321002,0.0001160017,0.0002918833,0.0001782744,0.0002912926,0.0005357499],"category_scores_gemma":[0.0001587929,0.000103601,0.0002870045,0.0001789769,0.00009318183,0.0001092095,0.0001338858,0.0004090434,0.0003402423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003415629,"about_ca_system_score_gemma":0.0001776728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001543587,"about_ca_topic_score_gemma":0.001117957,"domain_scores_codex":[0.9999229,0.00001155106,0.00000687321,0.00001634146,0.00002806213,0.00001431377],"domain_scores_gemma":[0.9999318,0.00001399507,0.000010792,0.00001195636,0.00001835339,0.00001305525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001145853,0.000007781566,0.0001087567,0.000007677,0.000001907762,0.00001514144,0.000006058649,0.0000285301,0.999347,0.00001046307,0.000009122175,0.000446139],"study_design_scores_gemma":[0.00001469688,0.0003871953,0.01016694,0.000007287337,0.00002714951,0.0004251114,0.00003838617,0.001473535,0.9830732,0.00003753377,0.004343621,0.000005372838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915913,0.0006109328,0.005807552,0.00009981091,0.00001532104,0.00006679875,0.0008154635,0.00006825721,0.000924518],"genre_scores_gemma":[0.9858449,0.0004975138,0.007016353,0.00009154026,0.00001018214,0.00004170735,0.003658162,0.00003142118,0.002808236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001543587,"threshold_uncertainty_score":0.003069222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082470946357555,"score_gpt":0.2182951564566715,"score_spread":0.207470446993096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}