{"id":"W1967925266","doi":"10.1179/1351000211y.0000000005","title":"Tyr<sup>740</sup>and Tyr<sup>751</sup>residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor","year":2011,"lang":"en","type":"article","venue":"Redox Report","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Alberta Health Services","funders":"","keywords":"Tensin; PTEN; Protein kinase B; Protein tyrosine phosphatase; Platelet-derived growth factor receptor; Phosphorylation; Chemistry; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Phosphatase; Receptor tyrosine kinase; Molecular biology; Biochemistry; Cell biology; Biology; PI3K/AKT/mTOR pathway; Signal transduction; Growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006841445,0.0003927418,0.00009072156,0.0001014195,0.0001436931,0.0001869952,0.0001627594,0.0001474875,0.002137409],"category_scores_gemma":[0.00008569792,0.00008524922,0.000111182,0.00009479342,0.0001958399,0.0001341026,0.0001066569,0.0002456031,0.000705077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002663064,"about_ca_system_score_gemma":0.000140072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004224366,"about_ca_topic_score_gemma":0.0005005498,"domain_scores_codex":[0.9999404,0.000009501981,0.000005341792,0.00001073888,0.00002199738,0.00001197173],"domain_scores_gemma":[0.9999576,0.000005326937,0.0000171785,0.00000360071,0.000005749217,0.00001061942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001131354,0.0000135607,0.0001614976,0.00002141673,0.000004314771,0.00009468465,0.000006484537,0.00005141115,0.9980199,0.0002686991,0.00007888295,0.001165968],"study_design_scores_gemma":[0.000009330002,0.00006611765,0.003742718,0.000003206136,0.00001140849,0.0004999284,0.00001808221,0.0004333178,0.9901592,0.0001125868,0.004941074,0.000003054116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920818,0.001208046,0.0027079,0.000165465,0.00005704656,0.00001494762,0.000425269,0.0000497235,0.003289765],"genre_scores_gemma":[0.9884323,0.0007826457,0.001782737,0.00006037625,0.00001786166,0.00002200054,0.001566691,0.0000201457,0.007315103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002137409,"threshold_uncertainty_score":0.007150412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0206005348017592,"score_gpt":0.2409222219030618,"score_spread":0.2203216871013026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}