{"id":"W1967925266","doi":"10.1179/1351000211y.0000000005","title":"Tyr<sup>740</sup>and Tyr<sup>751</sup>residues of platelet-derived growth factor beta receptor are responsible for the redox regulation of phosphatase and tensin homolog in the cells stimulated with platelet-derived growth factor","year":2011,"lang":"en","type":"article","venue":"Redox Report","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Alberta Health Services","funders":"","keywords":"Tensin; PTEN; Protein kinase B; Protein tyrosine phosphatase; Platelet-derived growth factor receptor; Phosphorylation; Chemistry; Tyrosine phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Phosphatase; Receptor tyrosine kinase; Molecular biology; Biochemistry; Cell biology; Biology; PI3K/AKT/mTOR pathway; Signal transduction; Growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007589922,0.0004851089,0.0006863681,0.0001475132,0.0001782994,0.00004261384,0.0004022196,0.0004662236,0.00004912329],"category_scores_gemma":[0.0005241121,0.0003253743,0.0001481069,0.000301823,0.0005996493,0.00004069542,0.0001555295,0.0002787273,0.00000115687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004717214,"about_ca_system_score_gemma":0.0003230114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004731703,"about_ca_topic_score_gemma":0.00006613965,"domain_scores_codex":[0.9970016,0.0002490782,0.0009606346,0.0008634648,0.0004212263,0.0005039979],"domain_scores_gemma":[0.9970485,0.0003449096,0.0009407296,0.0009619204,0.0005757516,0.0001281704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004310965,0.0001902296,0.01724533,0.0002497524,0.0004991117,0.0001472154,0.002570714,0.0004831346,0.9715288,0.00005215796,0.00127655,0.001446016],"study_design_scores_gemma":[0.001908406,0.001020259,0.03650039,0.0001608842,0.000111281,0.0002594169,0.0006165323,0.0004677127,0.9574216,0.0001859135,0.0009202012,0.0004273949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942935,0.003037703,0.0003986659,0.0002189049,0.00008775778,0.001410395,0.000480401,0.0000308705,0.00004179191],"genre_scores_gemma":[0.9957795,0.0009979227,0.00243552,0.00008710751,0.0001080244,0.0000810487,0.0003181044,0.00008310923,0.0001096462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01925506,"threshold_uncertainty_score":0.9999198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0206005348017592,"score_gpt":0.2409222219030618,"score_spread":0.2203216871013026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}