{"id":"W1967927207","doi":"10.1038/cmi.2010.59","title":"CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity","year":2010,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Microvesicles; Immunology; CD8; Immunity; T lymphocyte; Cellular immunity; Lymphocyte; Cell mediated immunity; Immune system; Chemistry; Biology; In vitro; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003225041,0.0004682129,0.0005180671,0.0002494194,0.0002658181,0.0006449429,0.0002465965,0.0007113052,0.00186739],"category_scores_gemma":[0.0004970536,0.000252249,0.0003448923,0.0001425043,0.0002741714,0.0005195079,0.0004032862,0.001432844,0.0005794935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002610715,"about_ca_system_score_gemma":0.0003547702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001373904,"about_ca_topic_score_gemma":0.0002235651,"domain_scores_codex":[0.9996512,0.0001042556,0.0000285628,0.00003114295,0.00006121266,0.0001235938],"domain_scores_gemma":[0.999742,0.0001150999,0.00003078184,0.00004523489,0.00002105223,0.00004583367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005301569,0.000926487,0.0009294425,0.0001619426,0.00005862113,0.0002051506,0.00004650608,0.0009888915,0.9701672,0.0008349102,0.0008304085,0.01954891],"study_design_scores_gemma":[0.0006704597,0.003159409,0.002706983,0.00001540354,0.00005382809,0.0003178601,0.00004479155,0.002785298,0.9861237,0.0004673912,0.00364366,0.00001124663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933241,0.002318056,0.001767167,0.0002001501,0.0002009559,0.0000532602,0.00009868334,0.0001010491,0.00193664],"genre_scores_gemma":[0.9955877,0.0006435534,0.0008572394,0.00008072916,0.00008235658,0.00005496804,0.0001660431,0.00001809883,0.002509376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00186739,"threshold_uncertainty_score":0.006247044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004243527146191548,"score_gpt":0.2152328441406371,"score_spread":0.2109893169944456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}