{"id":"W1967927207","doi":"10.1038/cmi.2010.59","title":"CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity","year":2010,"lang":"en","type":"article","venue":"Cellular and Molecular Immunology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Microvesicles; Immunology; CD8; Immunity; T lymphocyte; Cellular immunity; Lymphocyte; Cell mediated immunity; Immune system; Chemistry; Biology; In vitro; Biochemistry; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003482828,0.0004335273,0.0003602294,0.0001619891,0.0002897994,0.00008251947,0.0003897875,0.0004985669,0.00005309228],"category_scores_gemma":[0.0002551557,0.0004596088,0.0001603938,0.0001346025,0.0009022654,0.00001522979,0.0005772224,0.00047918,0.00002708358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001499273,"about_ca_system_score_gemma":0.0002024751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004586792,"about_ca_topic_score_gemma":0.00001568732,"domain_scores_codex":[0.9977666,0.0003269173,0.0003848525,0.0007781734,0.0001600783,0.0005833783],"domain_scores_gemma":[0.9983723,0.00004393021,0.0001560395,0.001074968,0.0001052351,0.0002475584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004142101,0.0001601416,0.001348531,0.00005162413,0.00009074108,0.0002416731,0.00005620885,0.000001247349,0.9957848,0.0004593396,0.00008786696,0.001303589],"study_design_scores_gemma":[0.001948473,0.0003419183,0.002284711,0.00001429486,0.00008104278,0.0002656446,0.0001055475,0.00003161707,0.9813201,0.0002764724,0.01281028,0.0005199202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.969725,0.02774069,0.0009989929,0.0001299766,0.0003059313,0.0003662745,0.00003348263,0.00005120705,0.0006484513],"genre_scores_gemma":[0.9959534,0.001378249,0.001120101,0.0003916602,0.00009182069,0.00004296816,0.0001955253,0.00008220244,0.0007440532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02636244,"threshold_uncertainty_score":0.9997855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004243527146191548,"score_gpt":0.2152328441406371,"score_spread":0.2109893169944456,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}