{"id":"W1967998659","doi":"10.1089/08892220050193047","title":"Activation and Regulation of Interferon Regulatory Factor 4 in HTLV Type 1-Infected T Lymphocytes","year":2000,"lang":"en","type":"article","venue":"AIDS Research and Human Retroviruses","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Tropical spastic paraparesis; Biology; Human T-lymphotropic virus 1; IRF1; Ionomycin; Interferon regulatory factors; Virology; Transcription factor; Interferon; T cell; Molecular biology; Cancer research; T-cell leukemia; Virus; Immunology; Gene; Cell biology; Genetics; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002908445,0.0001280227,0.0002540436,0.00036013,0.0002635047,0.00002138113,0.00008978917,0.0001781178,0.00096036],"category_scores_gemma":[0.00009612402,0.0001051677,0.00002367225,0.0002543056,0.0007109631,0.0001581887,0.00008475959,0.0002603332,0.00003686257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005343701,"about_ca_system_score_gemma":0.00004828305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009011114,"about_ca_topic_score_gemma":0.0002049811,"domain_scores_codex":[0.9988337,0.0002253984,0.0002503559,0.0002731254,0.00008309274,0.0003343019],"domain_scores_gemma":[0.9994029,0.0002110845,0.00005114935,0.0001785697,0.0001281802,0.00002808734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005709483,0.00009338252,0.237227,0.00005309678,0.00005873477,7.108476e-7,0.0005411832,4.846894e-7,0.7471861,0.001634001,0.0004750515,0.01215934],"study_design_scores_gemma":[0.001085063,0.001928629,0.7775737,0.00009561072,0.00000590075,0.000003283515,0.0002398174,5.415009e-7,0.2153631,0.0007983556,0.002788498,0.0001175104],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958212,0.00216078,9.00701e-7,0.00001978907,0.00004132712,0.0001788457,0.00000977626,0.00002797164,0.001739391],"genre_scores_gemma":[0.9946545,0.0007287616,0.000009933186,0.00001264972,0.00002476234,0.000007789045,0.00002401569,0.00001223474,0.00452535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5403467,"threshold_uncertainty_score":0.9999529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0491962874100669,"score_gpt":0.3192128966617197,"score_spread":0.2700166092516528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}