{"id":"W1968008033","doi":"10.1093/jnci/93.12.903","title":"Reovirus as an Oncolytic Agent Against Experimental Human Malignant Gliomas","year":2001,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre","funders":"","keywords":"Oncolytic virus; Glioma; In vivo; U87; Cell culture; Cancer research; Biology; Virology; Viral replication; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003552332,0.0005353308,0.000417849,0.0003652968,0.0001549608,0.0003138761,0.0003200974,0.000369824,0.0009817609],"category_scores_gemma":[0.0002137638,0.0001112393,0.0003053501,0.0001943497,0.0003538489,0.0002675803,0.0001974831,0.0007409214,0.0002308129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003748342,"about_ca_system_score_gemma":0.0003310279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027395,"about_ca_topic_score_gemma":0.001333064,"domain_scores_codex":[0.9997852,0.00005011008,0.00001742563,0.00003934198,0.00005417169,0.00005371661],"domain_scores_gemma":[0.9998449,0.00005328982,0.00002882773,0.00002597889,0.00001950749,0.00002735395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000846817,0.0005028611,0.0003785905,0.0001701465,0.00003087471,0.0001084638,0.00005573918,0.0003051857,0.9901528,0.0002609954,0.0001339968,0.007053535],"study_design_scores_gemma":[0.00009887616,0.004230864,0.001199335,0.00001405345,0.00004817856,0.0002832118,0.00001663573,0.0007135998,0.9914898,0.00002771307,0.00187346,0.000004299935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913822,0.003629397,0.003142965,0.000095326,0.00007924183,0.0001279675,0.0001886051,0.00009700064,0.001257333],"genre_scores_gemma":[0.992918,0.001659348,0.003664494,0.00002471247,0.00002726077,0.00007635083,0.0003812633,0.00002407825,0.00122457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001027395,"threshold_uncertainty_score":0.003284276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07050542648468706,"score_gpt":0.4076208752620286,"score_spread":0.3371154487773416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}