{"id":"W1968008033","doi":"10.1093/jnci/93.12.903","title":"Reovirus as an Oncolytic Agent Against Experimental Human Malignant Gliomas","year":2001,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre","funders":"","keywords":"Oncolytic virus; Glioma; In vivo; U87; Cell culture; Cancer research; Biology; Virology; Viral replication; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004939892,0.0001440096,0.0001418947,0.0001071781,0.0002597275,0.00004319412,0.0006005022,0.00008754226,0.000112836],"category_scores_gemma":[0.00006546114,0.0001053411,0.0001795649,0.0001840081,0.0001499086,0.0000307654,0.0001021123,0.000191313,0.00001019995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003884654,"about_ca_system_score_gemma":0.0009256837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004997135,"about_ca_topic_score_gemma":0.0003844172,"domain_scores_codex":[0.9982572,0.000105596,0.000354709,0.0001890525,0.0008754958,0.000217932],"domain_scores_gemma":[0.9989475,0.000005807237,0.0002645533,0.0001949968,0.0004418012,0.0001453288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001246325,0.0001934428,0.0003958922,0.00000342039,0.0001233387,0.00003605604,0.00006865702,0.00290083,0.9908765,0.0001414517,0.0027971,0.001216994],"study_design_scores_gemma":[0.001434496,0.001595748,0.0008373088,0.00004077281,0.00001596082,0.0002404016,0.00004568201,0.00003768712,0.8930552,0.0002437145,0.102287,0.0001659922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945854,0.001384614,0.00001182761,0.0005795054,0.0008642282,0.0001538277,0.00001949657,0.000004006691,0.002397104],"genre_scores_gemma":[0.9948502,0.0003328979,0.00005726167,0.001803352,0.001889486,0.00001740821,0.0000137879,0.00002009462,0.001015523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09948993,"threshold_uncertainty_score":0.4295684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07050542648468706,"score_gpt":0.4076208752620286,"score_spread":0.3371154487773416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}