{"id":"W1968009274","doi":"10.1016/s0006-2952(03)00207-7","title":"The fusion of IGF I with stromal cell-derived factor I or α1 proteinase inhibitor alters their mitogenic or chemotactic activities while keeping their ability to inhibit HIV-1-gp120 binding","year":2003,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Growth factor; Fusion protein; Haematopoiesis; Stromal cell; Cell culture; Biology; Insulin-like growth factor; Chemotaxis; Cell biology; Molecular biology; Biochemistry; Cancer research; Stem cell; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001362911,0.0004070441,0.0001704762,0.0002662328,0.0001766272,0.0003220454,0.0002082481,0.0002451653,0.001415569],"category_scores_gemma":[0.0002061139,0.0001267525,0.0002388478,0.0001915781,0.0003893369,0.0001946054,0.0001273308,0.0004781404,0.000303851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004383411,"about_ca_system_score_gemma":0.0003831042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003152268,"about_ca_topic_score_gemma":0.002980324,"domain_scores_codex":[0.999886,0.00001819834,0.00000756044,0.0000138842,0.00001922071,0.00005514679],"domain_scores_gemma":[0.9998471,0.00006111061,0.00002000189,0.00001602829,0.00001028918,0.0000455405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005639915,0.00004130163,0.000299375,0.0000258142,0.000007677386,0.00006847872,0.00001484047,0.0001528122,0.9966229,0.000274956,0.00008806319,0.001839703],"study_design_scores_gemma":[0.00001408964,0.000181906,0.001201961,0.000002071554,0.000007540391,0.0001235502,0.00002128502,0.0002383117,0.9962516,0.00003266702,0.001921183,0.000003748171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917117,0.001703149,0.001903467,0.0001537757,0.0001456893,0.00002947692,0.0004298825,0.00008923416,0.00383365],"genre_scores_gemma":[0.9943322,0.0007470275,0.001844861,0.0000612447,0.00002520802,0.00002058572,0.0005001546,0.00001726744,0.002451404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003152268,"threshold_uncertainty_score":0.006267846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02545308171090243,"score_gpt":0.2670306371582772,"score_spread":0.2415775554473748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}