{"id":"W1968018206","doi":"10.1371/journal.ppat.1000036","title":"A Novel Secretion Pathway of Salmonella enterica Acts as an Antivirulence Modulator during Salmonellosis","year":2008,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; University of British Columbia; Canadian Association of Gastroenterology; AstraZeneca; Howard Hughes Medical Institute","keywords":"Salmonella enterica; Salmonella; Secretion; Microbiology; Biology; Intimin; Bacterial outer membrane; Type three secretion system; Pathogenicity island; Enterobacteriaceae; Bacteria; Virulence; Escherichia coli; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008202164,0.0002341264,0.0001630174,0.0001236825,0.00009725015,0.000206893,0.00007202355,0.0001434482,0.0003961007],"category_scores_gemma":[0.00007712213,0.00009181361,0.0002199662,0.00007443057,0.0001264723,0.0001605988,0.0002471914,0.0002000356,0.0001384664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000152568,"about_ca_system_score_gemma":0.0001458004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002298669,"about_ca_topic_score_gemma":0.0002485526,"domain_scores_codex":[0.9999268,0.00001050926,0.000007733156,0.00001863506,0.00001679716,0.00001954568],"domain_scores_gemma":[0.9999418,0.000003353014,0.00001975257,0.00000424079,0.00001120041,0.00001963133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006849078,0.000003954406,0.0004171196,0.00001995923,0.000001307128,0.0000504409,0.000007583324,0.00001432357,0.9988729,0.00002396531,0.000008001645,0.0005119076],"study_design_scores_gemma":[0.00003932516,0.001012863,0.07457399,0.00002521582,0.00003249176,0.001039563,0.0002137023,0.002155175,0.918023,0.000145248,0.002723765,0.00001563273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967839,0.000930278,0.001588355,0.00004462035,0.00001130857,0.00001170002,0.0001081165,0.0000605536,0.0004612843],"genre_scores_gemma":[0.9977987,0.000346088,0.0008861322,0.00002286401,0.000004355848,0.000008654497,0.0002019507,0.000005649749,0.0007254914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003961007,"threshold_uncertainty_score":0.001325071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04262985238900787,"score_gpt":0.224045251041938,"score_spread":0.1814153986529301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}