{"id":"W1968049544","doi":"10.1016/j.pupt.2010.10.009","title":"Activation of the EP4 prostanoid receptor induces prostaglandin E2 and pro-inflammatory cytokine production in human airway epithelial cells","year":2010,"lang":"en","type":"article","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Cystic Fibrosis Foundation","keywords":"Receptor; Chemokine; Prostaglandin D2; Cell biology; Prostaglandin E; Cytokine; Chemistry; Prostaglandin E2 receptor; Agonist; Endocrinology; Internal medicine; Biology; Immunology; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005343828,0.0003399967,0.0005376716,0.0004160578,0.0003929903,0.0004383789,0.0002273518,0.0005230226,0.003842881],"category_scores_gemma":[0.0004820502,0.0003177483,0.0007858441,0.0004423762,0.0003116743,0.0003909184,0.0003873131,0.0008218369,0.001140522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003512671,"about_ca_system_score_gemma":0.0003812001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173737,"about_ca_topic_score_gemma":0.001072934,"domain_scores_codex":[0.999333,0.0002093722,0.00005059699,0.00004711959,0.0001223655,0.0002374831],"domain_scores_gemma":[0.9997731,0.0001043002,0.00001414429,0.00004367605,0.00003682198,0.00002796358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002107136,0.0002951251,0.0008610678,0.00009639387,0.0000262456,0.0006789783,0.0001153781,0.0001858381,0.9923103,0.000198492,0.0002555317,0.002869536],"study_design_scores_gemma":[0.000329614,0.003154565,0.02855089,0.00001719648,0.00008037787,0.0009764678,0.0004249105,0.00216753,0.9604628,0.0002641878,0.00355076,0.00002077029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953372,0.001132788,0.001162371,0.0001500552,0.00006622058,0.00005650038,0.000350368,0.00002172286,0.001722689],"genre_scores_gemma":[0.9922991,0.0009118739,0.001261667,0.0001709349,0.00007520886,0.0001222391,0.00135907,0.000009537617,0.003790302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003842881,"threshold_uncertainty_score":0.01285577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524225049652527,"score_gpt":0.2797526267555964,"score_spread":0.2645103762590711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}