{"id":"W1968119300","doi":"10.1210/en.2013-1410","title":"GATA4 and GATA6 Silencing in Ovarian Granulosa Cells Affects Levels of mRNAs Involved in Steroidogenesis, Extracellular Structure Organization, IGF-I Activity, and Apoptosis","year":2013,"lang":"en","type":"article","venue":"Endocrinology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Vector Institute","keywords":"Gene silencing; Apoptosis; Internal medicine; Endocrinology; Extracellular; GATA6; GATA4; Biology; Cell biology; Medicine; Transcription factor; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001449121,0.0004412631,0.0003541349,0.0002994013,0.0001791998,0.0002903778,0.000253531,0.0003896705,0.002091664],"category_scores_gemma":[0.0001175412,0.0002632268,0.0003368428,0.0001859754,0.0004537334,0.0002310555,0.0002829311,0.0007081682,0.0004461223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000272789,"about_ca_system_score_gemma":0.0002142586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007807788,"about_ca_topic_score_gemma":0.001132252,"domain_scores_codex":[0.9997198,0.00002829053,0.00003561824,0.00009210042,0.00005369998,0.00007046824],"domain_scores_gemma":[0.9998091,0.00002380346,0.00005806749,0.00002481528,0.0000163289,0.00006791219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131968,0.000008748464,0.0001780144,0.00002774244,0.000003558894,0.00002114379,0.00001089189,0.00002752623,0.9991838,0.0000503975,0.00002237561,0.0003337515],"study_design_scores_gemma":[0.00003906701,0.0001711168,0.007374723,0.000005811291,0.00002632016,0.0001540569,0.00005431018,0.0007227343,0.989223,0.00006373248,0.002159317,0.000005912157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934646,0.001274788,0.002405911,0.0001703175,0.00007013533,0.00002720481,0.001276078,0.0001180336,0.001192881],"genre_scores_gemma":[0.9866052,0.0008887654,0.004479961,0.0001653521,0.00002031262,0.00009656622,0.001665545,0.00007957665,0.005998735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002091664,"threshold_uncertainty_score":0.006997347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114097960783456,"score_gpt":0.239547527816169,"score_spread":0.2281377317378234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}