{"id":"W1968119300","doi":"10.1210/en.2013-1410","title":"GATA4 and GATA6 Silencing in Ovarian Granulosa Cells Affects Levels of mRNAs Involved in Steroidogenesis, Extracellular Structure Organization, IGF-I Activity, and Apoptosis","year":2013,"lang":"en","type":"article","venue":"Endocrinology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute; Vector Institute","keywords":"Gene silencing; Apoptosis; Internal medicine; Endocrinology; Extracellular; GATA6; GATA4; Biology; Cell biology; Medicine; Transcription factor; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008106265,0.0001737401,0.0002606474,0.0001991249,0.00003894624,0.00002259583,0.0001325571,0.0001734123,0.00007770599],"category_scores_gemma":[0.0001204549,0.000178962,0.00001978911,0.0002431454,0.0001469845,0.00001782478,0.0003279526,0.0001736445,0.000003155523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002148176,"about_ca_system_score_gemma":0.00006574378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000531107,"about_ca_topic_score_gemma":0.001409379,"domain_scores_codex":[0.9986738,0.0002064151,0.0001942746,0.0004268303,0.0001014773,0.0003972296],"domain_scores_gemma":[0.9994354,0.00006648725,0.0000578689,0.0002793038,0.00007945211,0.0000814438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002119169,0.00003320019,0.07230163,0.00009298199,0.00001764701,0.000009967948,0.0001327563,0.000007776083,0.9233915,0.00003081098,0.00001948106,0.003941054],"study_design_scores_gemma":[0.0007310393,0.0001358665,0.1757045,0.00001473447,0.000005791637,0.00002711912,0.000112603,0.00003821747,0.8229818,0.00008289856,0.00003308088,0.0001323216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977129,0.001541411,0.00009375442,0.0001099721,0.00005448162,0.000430589,0.00002886453,0.000006110932,0.00002197979],"genre_scores_gemma":[0.9992619,0.0003179538,0.0002387641,0.00002364722,0.00003206725,0.0000158427,0.00002269023,0.00002541852,0.00006175483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1034029,"threshold_uncertainty_score":0.729786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0114097960783456,"score_gpt":0.239547527816169,"score_spread":0.2281377317378234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}