{"id":"W1968120911","doi":"10.1158/1078-0432.ccr-14-1122-t","title":"A Recombinant Modified Vaccinia Ankara Vaccine Encoding Epstein–Barr Virus (EBV) Target Antigens: A Phase I Trial in UK Patients with EBV-Positive Cancer","year":2014,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; Institute of Cancer Research","funders":"Hong Kong Cancer Fund; Cancer Research UK; Wellcome Trust","keywords":"ELISPOT; Vaccination; Modified vaccinia Ankara; Virology; Antigen; Immunogenicity; Immunology; Vaccinia; Virus; Epitope; Biology; CD8; Medicine; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001025244,0.0007456459,0.001549836,0.0001856016,0.0002433727,0.0004893577,0.000552855,0.001063198,0.001454079],"category_scores_gemma":[0.0009676514,0.0003818155,0.0005786546,0.000318516,0.000586098,0.0005819153,0.0003528227,0.001625873,0.0003422965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008723372,"about_ca_system_score_gemma":0.0008348062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001443599,"about_ca_topic_score_gemma":0.001568544,"domain_scores_codex":[0.9996773,0.0001855124,0.00002126873,0.00004314838,0.00002313433,0.00004972585],"domain_scores_gemma":[0.9996131,0.00007590611,0.00008612306,0.00002652335,0.0000325232,0.000165825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6674239,0.02172049,0.01179858,0.002660285,0.001065821,0.001065378,0.0008566022,0.003473172,0.07172017,0.0002251211,0.002900404,0.2150901],"study_design_scores_gemma":[0.3515797,0.6087499,0.02707527,0.0001308696,0.0005443214,0.00105242,0.0001355316,0.00131859,0.004928984,0.00008694951,0.004363426,0.00003410591],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936924,0.004205109,0.0003611187,0.0002384812,0.00007991473,0.0006082838,0.0001334496,0.00004039806,0.0006408843],"genre_scores_gemma":[0.9940757,0.002706919,0.0006517211,0.0003356267,0.00007774006,0.0007598106,0.0004548873,0.00001109109,0.0009265674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001549836,"threshold_uncertainty_score":0.006329298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1073375662065019,"score_gpt":0.469174388612978,"score_spread":0.3618368224064761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}