{"id":"W1968173661","doi":"10.1016/s1471-4892(02)00138-8","title":"Vasopeptidase inhibitors: a new class of dual zinc metallopeptidase inhibitors for cardiorenal therapeutics","year":2002,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Neprilysin; Pharmacology; Medicine; Angiotensin-converting enzyme; Enzyme; Renin–angiotensin system; Chemistry; Endocrinology; Biochemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000592282,0.000965856,0.00399203,0.001541747,0.00008480014,0.00002917453,0.0002921009,0.0006875782,0.0008720584],"category_scores_gemma":[0.00008419649,0.0008247853,0.002583229,0.001320554,0.0002598379,0.0001425516,0.0001846713,0.001282608,0.0001189824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004464956,"about_ca_system_score_gemma":0.001088249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001211338,"about_ca_topic_score_gemma":0.000001870233,"domain_scores_codex":[0.9946408,0.0005175218,0.002457576,0.001018478,0.0005721945,0.0007934336],"domain_scores_gemma":[0.9970736,0.0004720432,0.001135631,0.0004929024,0.0002995452,0.0005262913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001364026,0.001318905,0.00001435869,0.03190169,0.001654072,0.00002290479,0.0001507761,0.00000824823,0.000189898,0.000105038,0.2149638,0.7495338],"study_design_scores_gemma":[0.004763689,0.0003852989,0.000001720675,0.02896757,0.004016614,0.0001205368,0.00002864587,0.0001629473,0.0002489971,0.00002483042,0.960638,0.0006411512],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005793074,0.991121,0.0001444398,0.0003594068,0.004571561,0.002923648,0.0004735128,0.00008972905,0.0002587776],"genre_scores_gemma":[0.0001532184,0.9906734,0.000241174,0.0001482511,0.005913761,0.0006123057,0.001577161,0.0001375437,0.00054319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7488927,"threshold_uncertainty_score":0.9994203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1689001591189125,"score_gpt":0.4422934700068716,"score_spread":0.273393310887959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}