{"id":"W1968182403","doi":"10.1016/j.coi.2007.09.002","title":"The inflammasome: a danger sensing complex triggering innate immunity","year":2007,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":699,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammasome; NALP3; Innate immune system; AIM2; Proinflammatory cytokine; Caspase 1; Biology; Interleukin 18; Inflammation; Immunology; Immunity; Cell biology; Immune system; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001203146,0.001502727,0.002569688,0.001389346,0.0003342085,0.002150232,0.001841165,0.002986368,0.002828444],"category_scores_gemma":[0.0009671943,0.0003821041,0.0004605126,0.00203212,0.00136476,0.003229881,0.001014475,0.004234403,0.004476652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008223825,"about_ca_system_score_gemma":0.001074752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003495966,"about_ca_topic_score_gemma":0.0005769314,"domain_scores_codex":[0.9996462,0.00004856095,0.00004591542,0.00006556108,0.0001658158,0.00002804369],"domain_scores_gemma":[0.9993926,0.0002119377,0.00008381631,0.00002388152,0.0001800674,0.0001076101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002280413,0.00006194557,0.0001577801,0.007760142,0.00007816344,0.0004461562,0.00004645371,0.0003218643,0.005503717,0.006575491,0.09264063,0.8861795],"study_design_scores_gemma":[0.00006151343,0.00006432929,0.0004072765,0.00099555,0.00006978492,0.001745563,0.00006086842,0.000121088,0.0008047173,0.005346171,0.9902976,0.00002548317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001271335,0.9942355,0.0007258821,0.001325625,0.002269993,0.000008564189,0.00002449222,0.00001989971,0.001262984],"genre_scores_gemma":[0.0006807717,0.9942138,0.0005576785,0.001187088,0.002109818,0.00001479191,0.00005689981,0.000003118874,0.001176062],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002986368,"threshold_uncertainty_score":0.009462118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08772629359527882,"score_gpt":0.3806428360255477,"score_spread":0.2929165424302689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}