{"id":"W1968186954","doi":"10.1002/stem.457","title":"Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity  ","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; Howard Hughes Medical Institute","keywords":"Biology; Wnt signaling pathway; Haematopoiesis; Stem cell; Myeloid; Progenitor cell; Cell biology; Hematopoietic stem cell; Population; Bone marrow; Lymphopoiesis; Immunology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008315786,0.0003182149,0.0001845462,0.0002199794,0.00009513082,0.0002474996,0.0001465889,0.0001680151,0.001023174],"category_scores_gemma":[0.00007709661,0.0001246163,0.0002601348,0.0001444778,0.0001178686,0.0001081135,0.0002033071,0.0003882315,0.0003636438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001831059,"about_ca_system_score_gemma":0.000207662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005661424,"about_ca_topic_score_gemma":0.001045916,"domain_scores_codex":[0.9999024,0.00001110859,0.00001316637,0.0000139952,0.00002823588,0.00003117821],"domain_scores_gemma":[0.9999248,0.00001188602,0.00002290517,0.00001014159,0.000005462103,0.00002483072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005485963,0.00001442345,0.0001627443,0.00001885415,0.000003149172,0.00004249124,0.00001020054,0.00003386957,0.9987831,0.0000646299,0.00001947227,0.0007922666],"study_design_scores_gemma":[0.00001641198,0.0001982462,0.005722809,0.000006168032,0.0000217738,0.0002458481,0.00002397952,0.0008654639,0.9904191,0.00004980884,0.002426848,0.00000361262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945169,0.00119819,0.00230285,0.00004314671,0.00001564916,0.00003415308,0.0004225277,0.000101761,0.001364868],"genre_scores_gemma":[0.994325,0.0008743594,0.001531496,0.00004230803,0.000006446294,0.0000444347,0.000758128,0.00002594247,0.002391991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023174,"threshold_uncertainty_score":0.003422856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353727533411411,"score_gpt":0.2280964140937943,"score_spread":0.2145591387596802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}