{"id":"W1968186954","doi":"10.1002/stem.457","title":"Wnt3a Activates Dormant c-Kit− Bone Marrow-Derived Cells with Short-Term Multilineage Hematopoietic Reconstitution Capacity  ","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; Howard Hughes Medical Institute","keywords":"Biology; Wnt signaling pathway; Haematopoiesis; Stem cell; Myeloid; Progenitor cell; Cell biology; Hematopoietic stem cell; Population; Bone marrow; Lymphopoiesis; Immunology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002375633,0.0002565691,0.0002261214,0.00005055209,0.000135525,0.00005082078,0.0001591994,0.0002664341,0.00005641878],"category_scores_gemma":[0.000007182763,0.0002161082,0.00009187499,0.00007602015,0.0001899692,0.00001079407,0.00006844422,0.0002264858,0.00003388792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001421521,"about_ca_system_score_gemma":0.00006772328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002031375,"about_ca_topic_score_gemma":0.0001416612,"domain_scores_codex":[0.998682,0.00005692093,0.0003010761,0.0004701396,0.0001716912,0.0003181245],"domain_scores_gemma":[0.9990578,0.0000224039,0.0001269283,0.0005269286,0.0001183464,0.000147562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006395666,0.00008058231,0.001940605,0.00005016943,0.00003047635,0.000007002639,0.00008827822,0.00008198014,0.9960419,0.00001817547,0.00004600553,0.00155085],"study_design_scores_gemma":[0.0004331593,0.000172233,0.000915755,0.00002378743,0.00003014591,0.00001185766,0.00005253188,0.0001170619,0.9945179,0.00001874513,0.003398125,0.0003086576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949298,0.0001976661,0.002527383,0.00002837494,0.000545854,0.000374936,0.00003552446,0.00002872753,0.001331763],"genre_scores_gemma":[0.9962636,0.0001600361,0.002712131,0.0000314258,0.0002098632,0.00002350089,0.00006632364,0.00003243834,0.0005007006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003352119,"threshold_uncertainty_score":0.8812636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01353727533411411,"score_gpt":0.2280964140937943,"score_spread":0.2145591387596802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}