{"id":"W1968214033","doi":"10.1038/ng.3165","title":"BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence","year":2014,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Swiss Cancer Research Foundation; Federalno Ministarstvo Obrazovanja i Nauke; Wellcome Trust; Deutsches Krebsforschungszentrum; Mäxi-Stiftung; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Epigenetics; Prostate cancer; Biology; Gene silencing; EZH2; Cancer research; Cancer; Chromoplexy; Genetics; Gene; PCA3","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002090688,0.0002331845,0.0002517445,0.0007458602,0.0003022458,0.0005492577,0.0003065302,0.0004136113,0.002096712],"category_scores_gemma":[0.0004999974,0.0002201386,0.0003405891,0.0007972813,0.0002297677,0.0001851184,0.0003899507,0.0004350255,0.0004841565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003173587,"about_ca_system_score_gemma":0.0001965654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001378787,"about_ca_topic_score_gemma":0.001347982,"domain_scores_codex":[0.9997967,0.00002952049,0.00001384423,0.00004132874,0.00008472313,0.00003395922],"domain_scores_gemma":[0.999708,0.00003308176,0.0001439328,0.00002057536,0.00003267253,0.00006170486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002246146,0.00009413967,0.3821548,0.0002471457,0.000611974,0.001788427,0.00009466698,0.0009038848,0.5767083,0.0006322683,0.002509655,0.03200859],"study_design_scores_gemma":[0.00006554669,0.0002010183,0.8929036,0.00001950536,0.0004119741,0.006639287,0.0001598736,0.003579953,0.08762988,0.0005614529,0.007803045,0.00002481448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904122,0.005271265,0.001490853,0.0003084326,0.00004917326,0.00001609981,0.001043693,0.00009462174,0.001313681],"genre_scores_gemma":[0.9977978,0.0005771237,0.0003764387,0.00004424935,0.00001207469,0.0000077998,0.0005564982,0.00001057256,0.0006174271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002096712,"threshold_uncertainty_score":0.007014215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009302377633928473,"score_gpt":0.2790816488418085,"score_spread":0.26977927120788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}