{"id":"W1968284649","doi":"10.1006/prep.2001.1470","title":"A Method for Expression and Purification of Soluble, Active Hsp47, a Collagen-Specific Molecular Chaperone","year":2001,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chaperone (clinical); Chemistry; Biochemistry; Cell biology; Molecular biology; Computational biology; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006132098,0.0002022605,0.0002189995,0.0001284786,0.0002063519,0.00004356023,0.000178681,0.000283755,0.00002884737],"category_scores_gemma":[0.0001691521,0.000185085,0.00005738876,0.0001649931,0.0001034207,0.00002577494,0.0001194077,0.00009484323,0.000002133016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001909064,"about_ca_system_score_gemma":0.00006161231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001326686,"about_ca_topic_score_gemma":0.00000179599,"domain_scores_codex":[0.9981689,0.0002745805,0.0003509532,0.0006544334,0.0002667759,0.0002843917],"domain_scores_gemma":[0.998832,0.00003717399,0.0001966273,0.0004949118,0.0002798059,0.0001594596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007264789,0.0001158905,0.00003251996,0.00009874039,0.00001209129,7.092506e-7,0.0001886889,0.000006375487,0.947053,0.000355724,0.0002608054,0.051149],"study_design_scores_gemma":[0.0009900902,0.000281999,0.0003326229,0.0001016927,0.000006916884,0.000009270909,0.0001610116,0.0004275642,0.9363911,0.0004119292,0.06069608,0.0001897267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6705882,0.003519531,0.3216147,0.0006632961,0.00003183762,0.003153914,0.00003194682,0.00002459219,0.0003719738],"genre_scores_gemma":[0.9060066,0.001465044,0.08971521,0.00003830983,0.00009304957,0.001718513,0.0001895465,0.00004182872,0.0007319089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2354184,"threshold_uncertainty_score":0.7547545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02625071461289792,"score_gpt":0.3170811175657943,"score_spread":0.2908304029528964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}