{"id":"W1968303842","doi":"10.1128/mcb.24.11.5016-5027.2004","title":"Multiple Genetic Pathways Involving the <i>Caenorhabditis elegans</i> Bloom's Syndrome Genes <i>him-6</i> , <i>rad-51</i> , and <i>top-3</i> Are Needed To Maintain Genome Stability in the Germ Line","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; U.S. Bureau of Land Management; National Institutes of Health","keywords":"Biology; Caenorhabditis elegans; Genetics; RecQ helicase; Genome instability; Homologous recombination; Mitotic crossover; Bloom syndrome; Gene; Meiosis; Mitosis; DNA damage; Mutation; Mutant; DNA repair; Cell biology; Molecular biology; DNA; Helicase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007481205,0.001059333,0.0002561236,0.0003609092,0.0004100624,0.0004017764,0.0003288516,0.0003855518,0.001057459],"category_scores_gemma":[0.00009105845,0.0002832429,0.0004235636,0.0001165092,0.0003531493,0.0002493319,0.0004051622,0.0005557344,0.0003093439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005287482,"about_ca_system_score_gemma":0.000411592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001837413,"about_ca_topic_score_gemma":0.003592324,"domain_scores_codex":[0.999848,0.0000102509,0.00001376815,0.00004824244,0.00004917419,0.00003046166],"domain_scores_gemma":[0.9998264,0.00001435812,0.00006973206,0.00001664796,0.00001557955,0.00005731474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005875775,0.00001606448,0.0003559705,0.0000322294,0.000006712793,0.0001199476,0.000008954433,0.0001001445,0.9982504,0.0001288139,0.00003677204,0.0008850951],"study_design_scores_gemma":[0.00002483061,0.0001844087,0.02531297,0.00002240676,0.00004281034,0.0005804966,0.00005049778,0.001462867,0.969263,0.00022736,0.002810983,0.00001727757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895103,0.001581585,0.005147321,0.0001407098,0.0000399248,0.00005140158,0.0008437525,0.0004159031,0.002269201],"genre_scores_gemma":[0.9893671,0.001220236,0.005268274,0.00009097931,0.000007553711,0.00005757628,0.0007117306,0.0000383634,0.003238255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001837413,"threshold_uncertainty_score":0.003836393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007551369919789747,"score_gpt":0.1931229923621464,"score_spread":0.1855716224423567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}