{"id":"W1968317318","doi":"10.1021/ol701496b","title":"Strain-Release Electrophilic Activation via <i>E</i>-Cycloalkenones","year":2007,"lang":"en","type":"article","venue":"Organic Letters","topic":"Inorganic and Organometallic Chemistry","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Electrophile; Adduct; Strain (injury); Conjugated system; Double bond; Nitrogen; Photochemistry; Carbonyl group; Medicinal chemistry; Organic chemistry; Catalysis; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001800669,0.0003159673,0.0002378258,0.00006005864,0.0001712438,0.00004173247,0.0003653715,0.0001976222,0.009040818],"category_scores_gemma":[0.00007438754,0.0003261639,0.0001140569,0.000344425,0.00009522048,0.0001662873,0.00006610341,0.0004347342,0.0002566816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003617248,"about_ca_system_score_gemma":0.0000723543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002514606,"about_ca_topic_score_gemma":0.000006994658,"domain_scores_codex":[0.9981019,0.000008667444,0.0003833898,0.000465309,0.0003576318,0.0006830467],"domain_scores_gemma":[0.9989911,0.0000883736,0.0001601568,0.000519191,0.00004514053,0.0001960894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003438235,0.00007439307,0.0002656882,0.00006150788,0.00006159909,0.00004337327,0.000155154,8.515756e-7,0.994712,0.00005812114,0.0008306511,0.003702286],"study_design_scores_gemma":[0.0005762844,0.000009311383,0.0006029427,0.00001681422,0.00003868902,0.00007999466,0.0001088461,0.00000743787,0.9928473,0.00007990772,0.005245281,0.0003872311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846689,0.00005742937,0.008463752,0.001708028,0.00009727945,0.00005943913,0.000009087745,0.000285667,0.004650432],"genre_scores_gemma":[0.9950744,0.00001325613,0.0002308951,0.003000577,0.0008417467,0.000003357214,0.0001062639,0.00008963352,0.0006398883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0104055,"threshold_uncertainty_score":0.9999191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004644715901374085,"score_gpt":0.1927259392645869,"score_spread":0.1880812233632129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}