{"id":"W1968359330","doi":"10.1136/gut.2006.107953","title":"Paraoxonase 1, 2 and 3 DNA variants and susceptibility to childhood inflammatory bowel disease","year":2006,"lang":"en","type":"letter","venue":"Gut","topic":"Paraoxonase enzyme and polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Paraoxonase; PON1; Oxidative stress; Inflammatory bowel disease; Pathogenesis; Inflammation; Genetic predisposition; Immunology; Pathophysiology; Disease; Reactive oxygen species; Medicine; Bioinformatics; Biology; Genetics; Gene; Internal medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006735586,0.0007520503,0.001016642,0.000668299,0.0008792296,0.0006169748,0.0005871156,0.006788273,0.00371372],"category_scores_gemma":[0.006131838,0.0002952466,0.0004013092,0.0005091604,0.000703076,0.0008729543,0.0002135308,0.003097112,0.0009233798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001008704,"about_ca_system_score_gemma":0.0004255021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002341013,"about_ca_topic_score_gemma":0.002588123,"domain_scores_codex":[0.9992718,0.0002940759,0.00007220129,0.000127662,0.0001325146,0.0001018165],"domain_scores_gemma":[0.9974933,0.001656743,0.000254712,0.00009428416,0.0002428486,0.0002581877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.003321521,0.0006030515,0.2460037,0.0008005528,0.0002368274,0.3314405,0.001027691,0.001402636,0.009056649,0.004167068,0.3324221,0.06951771],"study_design_scores_gemma":[0.001220451,0.001719699,0.2138266,0.0006932553,0.0004054663,0.6059806,0.001022856,0.01114972,0.004430976,0.01252842,0.1468403,0.0001816436],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3224615,0.01806282,0.001493386,0.6232442,0.009266519,0.000130875,0.0008776289,0.0002678586,0.02419523],"genre_scores_gemma":[0.860565,0.009785667,0.001959763,0.08359224,0.02777861,0.0001458675,0.0003221938,0.00005580658,0.0157949],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006788273,"threshold_uncertainty_score":0.01242363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005686297865960783,"score_gpt":0.2147814152573213,"score_spread":0.2090951173913605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}