{"id":"W1968403663","doi":"10.1002/cbic.201100203","title":"Tight Binding of Transition‐State Analogues to a Peptidyl‐Aminoacyl‐<scp>L</scp>/<scp>D</scp>‐Isomerase from Frog Skin","year":2011,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universität Wien; Medizinische Universität Wien; Austrian Science Fund","keywords":"Peptide; Dermorphin; Stereochemistry; Chemistry; Amino acid; Isomerase; Residue (chemistry); Biochemistry; Peptide sequence; Nonribosomal peptide; Transition state analog; Active site; Enzyme; Biosynthesis; Opioid peptide; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001505753,0.0002728725,0.0001801101,0.00008157563,0.000140269,0.0003924267,0.0002690797,0.0003037387,0.001371241],"category_scores_gemma":[0.0002546483,0.000144928,0.0001755851,0.00007006666,0.0002012425,0.0001592159,0.0001851645,0.0004424957,0.000463706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002743265,"about_ca_system_score_gemma":0.0001702952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006401879,"about_ca_topic_score_gemma":0.0005572716,"domain_scores_codex":[0.9998389,0.00003374187,0.00001399276,0.00003991112,0.00003703618,0.00003639688],"domain_scores_gemma":[0.9998723,0.00004311739,0.00002924148,0.00001364831,0.000009927757,0.00003181545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002029109,0.00003364731,0.0001139686,0.00003038442,0.000006128723,0.00005183373,0.00001629989,0.0001700748,0.9984004,0.00007428514,0.00002196774,0.0008781268],"study_design_scores_gemma":[0.00002427502,0.0003832168,0.0004207382,0.000002033019,0.000005094056,0.00009008855,0.000007024194,0.0005666198,0.9977889,0.00001545606,0.0006930777,0.000003415063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966174,0.0005673303,0.001441757,0.00004206145,0.00002128398,0.00003197975,0.00007760382,0.00005027131,0.001150318],"genre_scores_gemma":[0.9974895,0.0002219052,0.001174598,0.00003641835,0.00000789656,0.00001547627,0.0002106773,0.00001302006,0.0008305453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001371241,"threshold_uncertainty_score":0.004587233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01780303057363252,"score_gpt":0.2105874363167979,"score_spread":0.1927844057431654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}