{"id":"W1968413700","doi":"10.1016/s0163-7258(03)00086-x","title":"cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease","year":2003,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institutes of Health Research; Institute of Neurosciences, Mental Health and Addiction; Douglas Mental Health University Institute; McGill University","funders":"","keywords":"Proteomics; Computational biology; Neuroscience; Schizophrenia (object-oriented programming); Genomics; Biology; DNA microarray; Disease; Alzheimer's disease; Microarray; Bioinformatics; Data science; Computer science; Genetics; Gene; Psychology; Medicine; Gene expression; Genome; Pathology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001416543,0.0002955483,0.0004374566,0.00007011749,0.00006992379,0.00001197399,0.0002171261,0.0001454549,0.000002161812],"category_scores_gemma":[0.00000325878,0.0002049343,0.0000774639,0.0001145353,0.0002176588,0.000001755284,0.00007972109,0.0002109167,6.778417e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007785316,"about_ca_system_score_gemma":0.0000674332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001902637,"about_ca_topic_score_gemma":0.000003432362,"domain_scores_codex":[0.9986431,0.0003965638,0.0002683196,0.0004539657,0.00006457365,0.0001734527],"domain_scores_gemma":[0.9993297,0.00005660347,0.0001956924,0.0003447113,0.00001331149,0.00005991313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003416833,0.002435131,0.0001740771,0.0008017549,0.001318744,0.00001516799,0.0001652986,0.000002878733,0.005840336,0.0003133477,0.0006841858,0.9879074],"study_design_scores_gemma":[0.001733879,0.0009103221,0.0002685119,0.0002883092,0.00529152,0.0000322434,0.0001082963,0.00001409612,0.001237242,0.0005313081,0.9889721,0.0006122291],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01197357,0.9844337,0.00004752942,0.0003108106,0.00002868797,0.003083039,0.00006227585,0.00001341887,0.00004695252],"genre_scores_gemma":[0.04218188,0.9559233,0.0004200564,0.0006553769,0.00007760499,0.0005983876,0.00004493625,0.00006689255,0.00003161599],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9882879,"threshold_uncertainty_score":0.8356977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08297676102349129,"score_gpt":0.3732448144116917,"score_spread":0.2902680533882004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}